Omics - Resources

Spatial Revolution: Harnessing Spatial Technologies In The Clinic For A Healthier Tomorrow

Envisioning a future where spatial technologies pave the way for more accurate diagnoses, targeted treatments, and ultimately, improved patient outcomes. Download our eBook today!

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Top R&D Stories of 2023

Through captivating articles, insight pieces, and spotlight interviews, we delve into the remarkable innovations, breakthroughs, and scientific marvels that have defined the landscape of research over the past year.

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Spatial Biology

Pianno: a Model for the Annotation of Spatial Transcriptomics Data

The model has unveiled insights on the evolution and diversification of the cell types of the brain.

NGS & Clinical Diagnostics

Next-Generation Protein Sequencing Enhancements Since 2022 Breakthrough

NGS & Clinical Diagnostics

Peptide Barcodes for NextGeneration Protein Sequencing

NGS & Clinical Diagnostics

The Next-Generation Protein Sequencing™ Platform of the Future

NGS & Clinical Diagnostics

Real-time dynamic single-molecule protein sequencing on an integrated semiconductor device

NGS & Clinical Diagnostics

Platinum Analysis Software Data Sheet

NGS & Clinical Diagnostics

Comparison of Protein Sequencing Analysis of CDNF, IL6, and FGF2 on Platinum and Mass Spectrometry

NGS & Clinical Diagnostics

Harmonized Multi-Omics Data Analysis - How Does It Impact Pharmaceutical Research?

Harmonized multi-omics data analysis integrates diverse omics disciplines in pharmaceutical research, standardizing protocols for reproducibility and enabling transformative impacts on drug discovery.

NGS & Clinical Diagnostics

Roadblocks to the Sharing of Large Multi-Omics Datasets

More analysis means more data, and sharing multi-omics datasets can present challenges as well as blessings.

Single Cell Analysis

Research Spotlight: Multi-Omics Data Harmonization for SARS-CoV-2 Virus and Drug Target Identification

The approach to omic data analysis combines multiple types of omic datasets in the hope of understanding multiple layers of a biological system.

Spatial Biology

Post-Event Proceedings – Spatial Biology UK 2023

Concise and insightful summaries of presentations delivered by prominent thought leaders at Spatial Biology UK 2023.

NGS & Clinical Diagnostics

Post-Event Proceedings – NextGen Omics US 2023

Concise and insightful summaries of presentations delivered by prominent thought leaders at NextGen Omics US 2023.

Spatial Biology

Curio Bioscience Pen Partnership with DNAnexus, Simplifying Data Analysis in Spatial Transcriptomics

The partnership will allow Curio to give access to DNAnexus's bioinformatics platform to some of their customers.

Spatial Biology

The Future of Healthcare: Exploring the Latest Innovations in Spatial Imaging Techniques for Pharmaceutical Applications

Omics by Oxford Global explore the importance of medical spatial imaging, its applications in surgical planning and pharmaceutical research and the impact of Omics on spatial imaging techniques

Top R&D Stories of 2023

Spatial Biology

Spatial and Single Cell Transcriptomics Uncovers Mechanisms for Ischemic Stroke Recovery

A team at Southeast University in Nanjing, China have investigated mouse models of ischemic stroke cases.

Spatial Biology

Interview with Gabriela Kramer Marek, Associate Professor, Reader in Molecular Imaging at The ICR

Talking patient stratification for immunotherapies and imaging agents, investigating PD-L1, and the work of the ICR.

NGS & Clinical Diagnostics

Diagnostic Breakthroughs: How Multi-Modal Signatures in Healthcare are Transforming Diagnosis and Treatment

Multi-modal signatures in healthcare combine data from various sources for improved diagnosis and treatment. While offering comprehensive insights, challenges like data integration and ethical concerns need addressing.

Spatial Biology

Cutting-Edge Trends in Spatial Omics: Speaking to Jasmine Plummer, Director of the Center for Spatial Omics at St Jude Children’s Research Hospital

Jasmine Plummer is Director of the Centre for Spatial Omics at St Jude Children’s Research Hospital. We spoke to her about her work in new genomic technologies for disease treatment and development ahead of her opening keynote presentation at NextGen Omics US and Synthetic Biology US 2024.

Spatial Biology

Spatial Revolution: Harnessing Spatial Technologies In The Clinic For A Healthier Tomorrow

Envisioning a future where spatial technologies pave the way for more accurate diagnoses, targeted treatments, and ultimately, improved patient outcomes. Download our eBook today!

Spatial Biology

Spatial Transcriptomics Technologies: Current Trends and Analysis

While the landscape for spatial transcriptomics technologies is booming, it could face a bottleneck similar to that seen in scRNA-seq.

Single Cell Analysis

Transforming Biomarker Development for Immunotherapy through Single Cell Spatial Phenotyping

On-Demand Webinar with Aditya Pratapa, Senior Data Scientist & Amélie Viratham at Akoya Biosciences

Genome Editing

The Applications of CRISPR in Optimising Animal Models for Human Disease Research

CRISPR-based animal models expedite drug development by enhancing accuracy, replicating human physiology, reducing time and cost, aiding in predicting treatment efficacy, and addressing safety concerns in clinical trials.

NGS & Clinical Diagnostics

Caler AML MRD Comprehensive Solution

NGS & Clinical Diagnostics

Comparison of Protein Sequencing Analysis of CDNF

NGS & Clinical Diagnostics

First-Class Solutions from NGS Experts

NGS & Clinical Diagnostics

Human Leuokocyte Antigen Panel

NGS & Clinical Diagnostics

Introduction to the NEXome Core Panel

NGS & Clinical Diagnostics

Making the Most of Your Scientific Data

NGS & Clinical Diagnostics

Maximised Guide Detection, Maximised Discovery

NGS & Clinical Diagnostics

NadPrep ES Hybrid Capture Reagents

NGS & Clinical Diagnostics

NadPrep EZ DNA Library Preparation Module

NGS & Clinical Diagnostics

NanOnco Plus Panel v3.0

NGS & Clinical Diagnostics

Save on Sequencing Costs in RNA-Seq Gene Expression

NGS & Clinical Diagnostics

Sequence What Matters Most With RiboCop

NGS & Clinical Diagnostics

Sequencing a Single Library on Different Platforms

NGS & Clinical Diagnostics

Single Cell ATACseq at Scale

NGS & Clinical Diagnostics

Single Cell Methylation at Scale

NGS & Clinical Diagnostics

Single Cell RNAseq at Scale

NGS & Clinical Diagnostics

The Best Sequencing Results with CORALL RNA-Seq V2

NGS & Clinical Diagnostics

The Future of Multi-Omics Data

NGS & Clinical Diagnostics

Total Solution of Methylation Capture Sequencing Based on BS Conversion

NGS & Clinical Diagnostics

Unleash the Power of Proteomics in Your Lab

Spatial Biology

In Conversation With...Anthony Zucca, Technical Sales Specialist Manager, NanoString

In conversation with Anthony Zucca, Technical Sales Specialist Manager, NanoString

NGS & Clinical Diagnostics

AI “Nearly Twice as Good” at Grading Rare Cancer Aggression

New studies have found that AI can outperform humans in grading the aggression and severity of retroperitoneal sarcoma, suggesting big potential for radiomics in cancer diagnosis.

Single Cell Analysis

Transforming Pharmaceutical Research: Exploring the Fundamental Techniques in Single Cell Metabolomics

Single Cell Analysis

Comparing Mass Spectrometry and Single-Molecule Sequencing for Single-Cell Proteomics

Advancements in mass spectrometry and single-molecule sequencing should accelerate protein analysis, assisting in approaches for cancer research and accessible single-cell measurements.

Single Cell Analysis

In Conversation With... Fan Zhang, Assistant Professor at the University of Colorado

Here, we speak to Fan Zhang, Assistant Professor at the University of Colorado, about the applications of computational biology in studying disease behaviour.

Single Cell Analysis

10x Genomics and Single Cell RNA Sequencing: Interview with Philip Bischoff and Angela Churchill

Unlocking the potential for FFPE samples in advancing single-cell sequencing for tumour microenvironment research.

NGS & Clinical Diagnostics

How AI is Opening New Doors in Synthetic Biology and Drug Design

Deep learning and AI are enhancing synthetic biology's role in drug design, emphasising the necessity of quality data in constructing models for approaches such as genome mining and data deconvolution.

Navigating the Pharma R&D Regulatory Landscape 2023

Our 'Navigating the Regulatory Landscape' eBook has been designed to provide you with invaluable insights into the intricacies of regulations & policies surrounding the challenges and opportunities of Real-World Data, genome editing, biomedical informatics, manufacturing and many more.

Single Cell Analysis

Integrating Machine Learning into Single-Cell Omics Analysis

Machine learning methods can be hugely important in aiding the interpretation and integration of data generated through single-cell omics analysis, assisting in disease detection and modelling.

Spatial Biology

Breakthrough Drug Development: Key Technologies and Platforms for Spatial Transcriptomics

Spatial Biology

Antibody Validation for Chip Cytometry

Spatial Biology

Applied Spatial Context in Imaging Mass Cytometry

Spatial Biology

Automated Laser Microdissection for Proteome Analysis

Spatial Biology

Bio-Techne Portfolio Overview

Spatial Biology

Cancer Research - Fast and Reproducible Biomarker Discovery

Spatial Biology

CellScope - The Next Generation of Chip Cytometry Instrumentation

Spatial Biology

CRO Services for Spatial Biology and Single-Cell Omics

Spatial Biology

Cultrex Products for Physiologic Cell Culture Brochure

Spatial Biology

Essential Stem Cell and Organoid Culture Workflow Brochure

Spatial Biology

Evolve Your Protein Analysis With Simple Western

Spatial Biology

Hyperion XTi Imaging System - Faster Detection for Higher Throughput

Spatial Biology

Leica Laser Microdissection Systems and Solutions

Spatial Biology

Liquid Biopsy Solutions for Circulating Tumor Cell and Rare Cell Analysis

Spatial Biology

Mouse Immuno-Oncology IMC Panel Kits

Precision Spatial Biology with Orion

Spatial Biology

Reactive Tonsil H&E Staining Case Study

Spatial Biology

Six Reasons to Choose CYTOF Technology

Spatial Biology

The Organoid Handbook - Building Better Organoids

Spatial Biology

Unlock the Full Slide Context at Subcellular Resolutions

Spatial Biology

Welcome to the RNAscope Experience

Single Cell Analysis

AI Tool Could Predict Single Cell RNA Sequencing and Expression

A new AI model - scGPT - improves single cell RNA sequencing by predicting gene expression in individual cells, although it may be some time before it enters general use.

Spatial Biology

In Conversation with... Bryan Serrels, NanoString

In conversation with Bryan Serrels, Technical Sales Specialist, NanoString

Digital PCR

An Overview of Liquid Biopsy: Non-Invasive Approaches to Monitoring Tumour Condition

Liquid biopsy allows for the analysis of blood samples for tumour-related materials such as ctDNA and CTCs, aiding in the non-invasive monitoring of tumour progression.

NGS & Clinical Diagnostics

The Applications of AI Prediction in Spatial Imaging Approaches

Here, we look at the growing applications of AI-driven spatial imaging techniques in healthcare, focusing on interpreting the 3D genome through cell imaging. AI can assist in understanding intricate data patterns, enabling an improved understanding of cell behaviour and diseases.

NGS & Clinical Diagnostics

Artificial Intelligence in Mammography Could Double Breast Cancer Screening Efficiency

Results from a trial conducted in Sweden – the first of its kind – indicated that the use of AI in mammography screening is safe for general practice, and that this could be a huge boost to radiologists.

Spatial Biology

Spatial Imaging in Clinical Research: Opportunities and Challenges Associated with Spatial Data

Advances in spatial imaging have revolutionised disease analysis, revealing new therapeutic targets and biomarkers. However, efficiently interpreting the vast amount of data generated remains a challenge.

NGS & Clinical Diagnostics

Genome Sequencing Approaches: Choosing Between Long-Read and Short-Read Sequencing

Short-read sequencing approaches are highly accurate for small DNA sequences, while long-read sequencing allows for the study of complete genomes without fragmentation. Combining both approaches can address individual constraints and yield more comprehensive results in DNA analysis.

NGS & Clinical Diagnostics

How the $100 Genome Could Reshape the Sequencing Landscape

While the cost of genome sequencing has continued to decrease, the present landscape is still too expensive for the true potential of precision medicine to be fully realised. One potentially revolutionary approach involves the use of a mass-produced item to help reduce costs.

Single Cell Analysis

Fuelling New Discoveries by Combining Single Cell and Spatial Transcriptomics

On-Demand Webinar featuring Didem Arikaya, Sr. Product Manager, Software at 10x Genomics

Digital PCR

dPCR Market Trends and Predictions for Future Development

The applications and opportunities offered by digital polymerase chain reaction (dPCR) technology have provided new techniques for molecular diagnostics. With an estimated global market value of USD $1bn by 2032, the future looks promising for dPCR approaches.

Spatial Biology

CosMx Spatial Molecular Imager - The First Fully-Integrated Single-Cell Spatial Biology Solution

Spatial Biology

GeoMx Digital Spatial Profiler - Heterogeneity Resolved with Specificity

Spatial Biology

Metabolite Explorer - A Software Tool for Targeted Analysis of Mass Spectrometry Imaging Data

Spatial Biology

NanoVIP - All-In-One, Fully Automated, Plug & Play

NGS & Clinical Diagnostics

Chronic Stress Found to Worsen Gut Inflammation

Research from the University of Pennsylvania suggests that stress levels may have a profound impact on the efficacy of treatment approaches for bowel disease.

Spatial Biology

In Conversation with Martin Hanczyc, Principal Investigator at the University of Trento

Amongst the hundreds of avenues of scientific discovery being pioneered today, one of the most compelling by far is that of artificial life. Synthetic biology forms a major branch of this.

Spatial Biology

A Deeper Discussion About The 10x Genomics Xenium In Situ Analyzer For In Situ Analysis

In conversation with Adrian Benjamin, Head of Global Product and Segment Marketing, 10x Genomics

Spatial Biology

Spatial Profiling, Analytical Approaches, and New Transcriptomic Technologies

Recent advances in spatial transcriptomics have facilitated the development of advanced techniques for uncovering new information about the cellular microenvironment. Two techniques explored here – Giotto and Slide-seq – are on the cutting edge of spatial imaging.

Genome Editing

Celebrating the Achievements of Barbara McClintock, Discoverer of Mobile Genetic Elements and Gene Transposition

To date, 114 Nobel Prizes in Physiology or Medicine have been awarded to 226 laureates. Of these laureates, just 12 have been women. This article looks at one of those 12 women and celebrates her contributions to the field of genetics. Her name is Barbara McClintock.

Genome Editing

New Human Pangenome Capturing More Genomic Diversity Released

The human pangenome contains genetic data from 47 people across Africa, Asia, Europe, and the Americas, and offers a more holistic cross-section of the planet’s genetic diversity.

Spatial Biology

Advanced Data Analysis Pipelines for Spatial Transcriptomics

Key opinion leaders discuss analysis pipelines for spatial transcriptomics analysis and the challenges faced in this field.

NGS & Clinical Diagnostics

20 Years Ago This Month: Human Genome Project Sequences 92% of the Human Genome

After 13 years of collaborative efforts, an international team of scientists and researchers had an announcement to share with the world. It was one that had major implications for the future of DNA sequencing and healthcare at large.

Spatial Biology

High Impact Publications with the Halo Image Platform

Spatial Biology

Human Advanced Cell Classification Panel

Spatial Biology

Hyperion XTi Imaging System

Spatial Biology

IMC Cell Segmentation Kit

Spatial Biology

Immuno-Oncology Panel Kits for Imaging Mass Cytometry

Spatial Biology

MIBI-Enabled Tissue Imaging and Analysis

Spatial Biology

MIBI-Validated Antibodies for Spatial Proteomics

Spatial Biology

Mouse Advanced Cell Classification Panel

Spatial Biology

Mouse Immuno-Oncology IMC Panel Kits

Spatial Biology

Multiplexed Imaging and Quantitative, Spatial Cell Phenotyping

Spatial Biology

The Cytof Advantage

NGS & Clinical Diagnostics

Untargeted Metabolomics Data Analysis Reinforced by AI/ML Techniques

A key utility of untargeted metabolomics is for detecting key metabolites as indicators of human health and disease status. AI/ML approaches can help to accelerate the verification and validation of metabolomics data.

Spatial Biology

Xenium: high performance in situ analysis

In Conversation With Michael Schnall-Levin, Chief Technology Officer & Founding Scientist, 10x Genomics

NGS & Clinical Diagnostics

Asteria - Advanced Single-Cell Analysis in a Straightforward Benchtop Kit

NGS & Clinical Diagnostics

Bio-Teche Launches RNAscope Plus Assay

NGS & Clinical Diagnostics

Chart the Unexplored Depths of Spatial Biology with AtlasXomics

NGS & Clinical Diagnostics

Combining Detection of Small Regulatory RNA with Target RNAs

NGS & Clinical Diagnostics

CosMx Spatial Molecular Imager - The First Fully-Integrated Single-Cell Spatial Biology Solution

Generating Clinically Relevant Insights from Single-Cell Data

NGS & Clinical Diagnostics

Genome-Wide Detection of all Structural Variants

NGS & Clinical Diagnostics

Genomic Scar Analysis for Homologous Recombination Deficiency with NxClinical Software

NGS & Clinical Diagnostics

Hematological Malignancies and Solid Tumour Research

NGS & Clinical Diagnostics

Investigating the Cellular Diversity of Breast Tissue with PIPSeq

NGS & Clinical Diagnostics

Optical Genome Mapping and Next Gen Sequencing

NGS & Clinical Diagnostics

PIPseq 3' Single Cell RNA Kits v4.0 for Gene Expression Analysis

NGS & Clinical Diagnostics

PIPseq Reveals Neuronal and Glial Cell Diversity in Freshly Dissociated Mouse Brain

NGS & Clinical Diagnostics

Reveal More Genomic Variation With Optical Genome Imaging

NGS & Clinical Diagnostics

RNAscope HiPlex v2 Assay - Enhancing Spatial Genomics

NGS & Clinical Diagnostics

RNAscope Multiplex In Situ Hybridization Technology

NGS & Clinical Diagnostics

Simultaneous Visualisation of RNA and Protein Targets

NGS & Clinical Diagnostics

Single Cell ATACseq at SCALE

NGS & Clinical Diagnostics

Spatial Profiling of Immune Cell Gene Signatures in the Tumour Microenvironment

NGS & Clinical Diagnostics

Vivid Fluorescent Dyes for Spatial Biology

Spatial Biology

Interview with Ahmet Coskun, Professor at Georgia Institute of Technology

We ask Ahmet Coskun, Professor at Georgia Institute of Technology, “what’s next for the future of spatial omics?”

Genome Editing

Transforming Genomics with AI

Artificial Intelligence (AI) and accelerated computing enable new frontiers in genome sequencing workflows.

Spatial Biology

Interview with Shirin Elizabeth Khorsandi, Adjunct Senior Lecturer at Kings College London

Shirin Elizabeth Khorsandi, Adjunct Senior Lecturer at King’s College London, talks about the future of AI for spatial omics.

Spatial Biology

Make Your Impact In Spatial Biology Now With NanoString

In Conversation With Espy Anguiano, PhD, MS-MBA

Genome Editing

On & Off-Target Genome Editing Techniques

Richard Stanton, Professor of Virology at Cardiff University, presents the latest on and off-target genome editing techniques.

Genome Editing

Machine Learning Algorithm Measures Prime Editing Efficiency

Wellcome Sanger Institute propose a new machine learning algorithm for predicting genome editing efficiency for the CRISPR-Cas9-based approach of prime editing.

Genome Editing

Recent Advances and the Future Landscape of Genome Editing For Disease Models And How This Has Helped Us Gain Insight Into Disease Biology

In Conversation With Laralynne Pryzbyla, Adjunct Assistant Professor at UCSF & UC Scientific Director, Laboratory for Genomics Research

Spatial Biology

Regulation & Policy: Interview with Arvind Rao, Associate Professor of Biostatistics at the University of Michigan

Arvind Rao, Associate Professor of Biostatistics at the University of Michigan, discusses the regulatory challenges and opportunities of biomedical informatics.

Genome Editing

Regulation & Policy: Interview with John Parrington, Associate Professor of Cellular and Molecular Pharmacology, University of Oxford

John Parrington, Associate Professor of Cellular and Molecular Pharmacology & Fellow of Worcester College, University of Oxford, discusses the regulatory challenges and opportunities of genome editing.

Single Cell Analysis

Navigating Post-Translational Modifications in Single-Cell Analysis

What are the current opportunities and challenges facing single-cell analysis today? We ask key opinion leaders from Janssen Pharmaceuticals, SciLifeLab, and the Karolinska Institutet.

Genome Editing

Policy Issues for Responsible Genomics Research

Responsible genomics research is vital to ensuring the advancement of health for society. But what are the ethical, social, and legal considerations that go into genomics-based decision making?

NGS & Clinical Diagnostics

Long-Read Sequencing Named 'Method of the Year 2022'

Powering a more complete reading of genomic information, Nature hails long-read sequencing as the omics-based method of the year.

Spatial Biology

The Future of Spatial Technology, Analysis, and Imaging

This Insight Article looks at the short and long-term predictions for spatial technological regulation, standardisation, and collaboration for the omics field.

NGS & Clinical Diagnostics

FDA Clears Genomic Profiling Test for Solid Tumours

Regulatory approval for comprehensive genomic profiling test signifies “significant advancement in personalised cancer care.”

Genome Editing

FDA and NIH Sign Interagency Collaboration Agreement to Advance Proteogenomics Research

A memorandum of understanding has been reached between the U.S. Food and Drug Administration (FDA) and the National Cancer Institute (NCI) to provide a framework for solving complex problems in molecular characterisation and classification of tumours.

Genome Editing

Novel Genome Editing Techniques: What Will Come Next after CRISPR-Cas9?

The gene editing field has exploded in the last ten years, with methods such as CRISPR-Cas9 becoming well-established in the pre-clinical sphere. However, complications in clinical applications have led some researchers to explore alternatives.

Spatial Biology

Rapid Development of Spatial Signatures as Predictive Biomarkers for Immunotherapy Response

On-Demand Webinar featuring Dr Alessio Colombo, Application Scientist at Akoya

Genome Editing

Genome Editing Technologies: Pioneering Approaches in Healthcare

Current and upcoming gene editing technologies, such as prime editing and cell line models, have huge potential in applications such as cancer treatment. With the field constantly witnessing new breakthroughs and advances, genome modification holds a lot of promise for the future.

NGS & Clinical Diagnostics

Spatial Analysis of TME Microglia in Melanoma Brain Metastasis

The therapeutic targeting of TME microglia activity may improve the efficacy of treatments for melanoma brain metastasis. Future research could represent a new opportunity in confronting one of the most difficult cancers to treat.

Spatial Biology

The Spatial Biology Week 2022. Watch now on-demand

Your front-row seat to world innovators

Spatial Biology

Spatial Omics Technologies: Spatial Proteomics, Mass Spectrometry, and Imaging Data Uses

Visualising and monitoring protein localisation requires a high degree of accuracy in image processing. Fortunately, spatial proteomics is proving itself to be an imaging technique which is more than up to the challenge.

Genome Editing

Building on a New Approach to Validate Gene Editing and Localize CAR Cassettes in T Cells

On-Demand Webinar featuring Dr. Peter Mouritzen, Vice President of Application and Market Development at Samplix ApS

Oxford Global's R&D Key 40 Stories 2022

Download a copy of the R&D Key 40 Stories 2022 ebook today.

Spatial Biology

Proteomics and Metabolomics: The Role of Cellular Microenvironment in Driving Tumour Progression and Metabolomic Fingerprint

Some of the investigative methods explored in this article include mass spectrometry imaging and cell modelling of tumour architecture.

NGS & Clinical Diagnostics

Antibody-Mediated Rejection and Next-Gen Sequencing in Precision Medicine

Maintaining tolerance to a graft or organ transplant is a critical aspect of treatment for precision medicine. Antibody-mediated rejection is a serious hurdle to transplantation success, but the integration of highly selected stem cells into treatment may be a solution.

Single Cell Analysis

Utilising Single-Cell Metabolomics to Reveal Metabolic Cell States

Single-cell metabolomics is a rapidly growing area of study within the field of molecular imaging. By applying metabolomic imaging techniques at a single-cell resolution, it can be used to investigate cellular progression in diseases such as NASH and liver cirrhosis.

Single Cell Analysis

Current Bioinformatics Trends in Single-Cell Data Analysis: Good Practice Makes Perfect

Good quality samples are integral to single-cell data analysis, but maintaining sample integrity presents a logistical hurdle for bioinformatics teams worldwide. Read on to learn about how senior healthcare researchers circumvent the issues associated with sample degradation.

Single Cell Analysis

Single-Cell Transcriptomics and Implications for COVID-19 Severity

The expression of the protein coding gene CXCR6 was observed to be significantly lower in patients with severe cases of COVID-19, suggesting a genetic correlation in severe cases.

Spatial Biology

Beyond Bioinformatics - Aspect Analytics

Spatial Biology

Bridging histology and genomics - Visium CytAssist

Spatial Biology

CELESTA Light Engine - Lumencor

Spatial Biology

Chromium X - The Most Flexible Way to Single Cell

Spatial Biology

Hyperion+ Imaging System

Spatial Biology

Maxpar OnDemand Mouse Immuno-Oncology Panel Kit

Spatial Biology

Molecular Cartography - Resolve Biosciences

Spatial Biology

Simultaneous Transcriptome and Epigenome Profiling - 10x Genomics

Spatial Biology

Single Cell Profiling without Time Constraints - 10x Genomics

Spatial Biology

Spatial Biology: A Buyer's Guide - Resolve Biosciences

Spatial Biology

SPECTRA Light Engine - Lumecor

Spatial Biology

The Hyperion and Hyperion+ Imaging Systems

Spatial Biology

Xenium Analyzer - In Situ Analysis of Cells

Spatial Biology

ZIVA Light Engine - Lumencor

Spatial Biology

Spatial Data: Computational Methods and Deep Learning-Based Models

In this Commentary article, we explore how the current boom in AI is enabling researchers to take bold new steps in data analysis, with the potential for its utilisation in coordinating new healthcare responses. Trusted research environments have increased the feasibility of using translational research to help tackle new and approaching problems in healthcare.

NGS & Clinical Diagnostics

Data Collection, Image Modelling, and Spatial Analysis: Quality Control for Quality Data

The potential applications of deep learning tools in preliminary studies have developed along with their complexity in the past few years. Now, they could be used to help to refine a study or programme before it takes place in order to optimise its efficiency.

Spatial Biology

Spatial Multiomics Symposium

Presented by experts from NanoString, Weill Cornell Medicine, St. Louis University School of Medicine, University of Queensland, Wake Forest University of Medicine & Brigham and Womens Hospital

NGS & Clinical Diagnostics

Next Generation Nucleic Acid Extraction for NGS: Increased Yields and More Efficient Workflows for Extraction from FFPE

On-demand seminar. Learn more about the Ionic system and a real-world case study on how the Ionic is being utilized at a leading cancer centre.

NGS & Clinical Diagnostics

Data Integration in Genomic Analysis: Computational Methods for the Integration of Spatial Metabolomics

This Commentary article explores the potential applications which arise from combining multiple modalities of information to augment the spatial resolution of data.

Single Cell Analysis

Sparsely Connected Autoencoders: A Multi-Purpose Tool for Single Cell Omics Analysis

In this Commentary article, we explore the opportunity afforded by Sparsely Connected Autoencoders to transform data in a controlled way to enable the comprehension of hidden biological information in single-cell data. Autoencoders provide researchers with a simplified means of inspecting functional relationships among regulatory elements as transcription factors.

Spatial Biology

Mass Spectrometry: Modern Medicines Swiss Army Knife

This Insight article explores some of the key applications of mass spectrometry imaging across the medical and pharmaceutical landscape. With the field seeing constant rapid development, mass spectrometry is an essential tool for current and future research in healthcare.

Single Cell Analysis

Single Cell Analysis of the Tumour Microenvironment: Improving Understandings of Immune Contexts

This Discussion Group Report investigates some of the various applications of single cell analysis, and explores the differences in its utility relative to other analysis techniques such as spatial transcriptomics.

Spatial Biology

Event Showcase: Sequencing the Future at Spatial Biology Europe

Miao-Ping Chien, Principal Investigator at Erasmus University Medical Center and Oncode Institute, explains what the Berlin meet has to offer and outlines her predictions for the future of spatial technology.

Genome Editing

Advances in Long Read DNA Sequencing

Long Read DNA Sequencing has the potential to help diagnose several diseases and disorders. Recent advancements mean that long-read sequencing is no longer an expensive, low throughput, error-prone process.

Spatial Biology

Spatial Analysis of the Tumour Microenvironment: Key Perspectives and New Areas of Focus

In this Insight article, we explore some of the challenges and new innovations concerning spatial analysis of the tumour microenvironment. One of the key focuses for ongoing studies is the retention of spatial information, which enables researchers to identify distinct tumour subtypes.

NGS & Clinical Diagnostics

Long and Short Read Sequencing: Revolutions in Genomics Data

In this Discussion Group Report, we investigate some recent applications of long- and short-read sequencing technologies. Continued improvements and advancements in the field mean sequencing errors are increasingly a thing of the past, while the portability of some new units makes them ideal for work in the field.

Spatial Biology

Assessment of Reproducibility in Multiplex Immunohistochemistry Application

Spatial Biology

Bridging Histology and Genomics

Spatial Biology

Comet - Accelerating Spatial Biology

Spatial Biology

Deep Spatial Phenotyping for 'Hallmarks of Cancer'

Spatial Biology

High Antibody Elution Efficiency Through Hyperplex Immunofluorescent Stainings

Spatial Biology

IMC Segmentation - A Cutting-Edge Approach to Improved Segmentation for High-Multiplex Analysis

Spatial Biology

Immuno-Oncology Panel Kits for Imaging Mass Cytometry

Spatial Biology

Ionpath High-Definition Spatial Proteomics

Spatial Biology

Ionpath Spatial Proteomics Pilot Program

Spatial Biology

KRAS Inhibition and Dramatic Remodelling of the Lung TME

Spatial Biology

Maxpar Antibodies for Imaging Mass Cytometry

Spatial Biology

Molecular Atlassing with MERSCOPE

Spatial Biology

Naveni PD1 and PD-L1 - Bringing Precision to Spatial Proteomics

Spatial Biology

Naveni PTM - Bringing Precision to Spatial Proteomics

Spatial Biology

NaveniBright - Bringing Precision to Spatial Proteomics

Spatial Biology

NaveniFlex - Bringing Precision to Spatial Proteomics

Spatial Biology

Orion Platform - Spatial Biology Realised

Spatial Biology

Single Cell and Spatial Technology to Accelerate Biological Insights

Spatial Biology

Spatial Biology Without Limits - Spatially Resolve Gene Expression in FFPE Samples

Spatial Biology

The Chromium X Technology Advantage Behind Single Cell

Spatial Biology

The RNA Revolution - A Guide to RNA as a Biomarker and its Detection

Spatial Biology

Transformative Multiplexed Tissue Imaging Platform that Delivers Actionable Information

Spatial Biology

Validated Antibody Panels for Ionpath Spatial Proteomic Services

Spatial Biology

Visualize Gene Expression Within the Tissue Context

NGS & Clinical Diagnostics

Paving the Road to Multi Omics Bioinformatics

Our May Omics Series discussion group focused on the current uses and potential of multi-omics bioinformatics.

Single Cell Analysis

Single Cell Proteomics: Advancements and Potential

Our April 2022 Omics Series discussion group focused on the potential and future of single-cell proteomics.

Spatial Biology

Omics US 2022: The Epicentre of the Spatial Omic Conversation

Showcasing the highlights from NextGen Omics: In-Person 2022. We asked Alex Tamburino, Associate Principal Scientist at Merck about his experience at the event.

Spatial Biology

Spatial Single Cell Metabolomics | Mass Spectrometry & Microscopy Integration

In Conversation With Theodore Alexandrov, Team Leader, European Molecular Biology Laboratory

Genome Editing

Showcasing Bleeding-Edge Genome Editing Companies: NextGen Omics US

Gábor Balázsi, Henry Laufer Professor of Physical and Quantitative Biology at Stony Brook University, takes us through the most valuable features that NextGen Omics US brought us in 2022.

NGS & Clinical Diagnostics

De Novo Variants: Genomic Sequencing and Problem Solving for Future Treatments

In this Commentary article, we investigate the application of new research techniques to inspecting genomic data for the presence of de novo variants - genetic alterations present for the first time in one individual as a result of a variant inherited from a parent. Used in combination with data from the 100,000 Genome Project, these techniques could reduce the time taken for patients to receive a diagnosis for rare genetic diseases.

Spatial Biology

A Spatial Examination of The Brain - From Development To Disease At The Subcellular Level

Rebus Biosystems has assembled five collaborators to share aspects of their cellular examinations of the human brain. From new strides in understanding brain development to exploring the sub cellular details of disease, these presentations illustrate the array of knowledge gained through cellular spatial exploration.

Digital PCR

Exploring Advanced Multiplex Assays

This month’s discussion was led by Pieter van der Velden. Topics included improving multiplex assays, T-Cell quantification and DNA methylation.

Single Cell Analysis

Single Cell Proteomics: Sample Preparation and Tissue Selection

Single-cell proteomics has developed quickly, despite being a relatively new field. NanoPOTS and FACS are being used to improve proteome coverage and minimise sample size.

NGS & Clinical Diagnostics

Multi-Tissue Molecular Profiling: Precision Medicine for Neurodegenerative Diseases

At NGO US: In-Person 2022, Carlos Cruchaga of the Washington School of Medicine presents on using QTL and GWAS data to unlock the future of therapeutic treatment for neurodegenerative disease.

Spatial Biology

Context Matters - Visualise RNA Localisation In-Situ at Subcellular Resolution

Spatial Biology

Esper High Fidelity Assay

Spatial Biology

High Impact Publications with the Halo Image Analysis Platform

Spatial Biology

Infographic - Spatial Transcriptomics

Spatial Biology

Introducing the CosMx Spatial Molecular Imager

Spatial Biology

Ionpath - High Definition Spatial Proteomics

Spatial Biology

Ionpath Spatial Proteomics Pilot Program

Spatial Biology

Quantification of Gene Expression Changes in Mouse Disease Models

Rebus Esper - Spatial Omics Platform

Spatial Biology

RNAscope ISH Application Gene Therapy Bio-Distribution Flyer

Spatial Biology

Simultaneous Visualization of RNA and Protein Targets Using the New Co-Detection Kit Flyer

Spatial Biology

Spatial Biology - A Buyer's Guide

Spatial Biology

Synthetic Aperture Optics

Spatial Biology

The Flow Cytometry Handbook - BioTechne

Spatial Biology

The Organoid Handbook - Building Better Organoids

Single Cell Analysis

Towards a Single-Cell Atlas of the Mouse Brain Using an Automated Spatial Omics Platform

Spatial Biology

Transformative Multiplexed Tissue Imaging that Delivers Actionable Information

Spatial Biology

Unravelling the Cellular and Subcellular Landscape Using Spatial Biology

Spatial Biology

Validated Antibody Panels for Ionpath Spatial Proteomic Services

Spatial Biology

Visualisation of In Vivo Gene Editing Heterogeneity at the Transcript Level with BaseScope Duplex RNA in situ Hybridization Assay

Spatial Biology

Visualization of Lgr5+ Stem Cells and the Immune Response in the Inflamed Mouse Colon by the RNAscope In Situ Hybridization Assay

Digital PCR

ddPCR: Exploring the Progress of PCR Technology and Novel Applications

Explore the history of PCR and how digital droplet PCR is being used for COVID-19 research.

Spatial Biology

Spatial Transcriptomics: Innovations & Novel Tools

With the development of single-cell RNA sequencing, it became possible to measure transcriptomes at a single-cell resolution. Is spatial transcriptomics the next step on the journey of understanding human biology?

Spatial Biology

Single-Cell Spatial Phenotyping: Setting the Pace of Discovery Biology

Presented by Oliver Braubach, Ph.D.Head of Applications at Akoya Biosciences Inc.

Spatial Biology

Understanding COVID-19 & The Immune Systems Response To Vaccines - A 10x Genomics Review

In Conversation With Rea Dabelic, PhD, Senior Market Development Manager in Immunology, 10x Genomics

Genome Editing

Novel System for Mice Sperm Cryopreservation Using Multilayer Insulation and Liquid Nitrogen

We sat down with the Co-director of Yale Genome Editing Centre of Yale University, Xiaojun Xing, to discuss his breakthrough cryopreservation method and his thoughts on the genome editing landscape.

Spatial Biology

Spatial Biology: Key Questions for the Future

Our February discussion group bought together more than 40 key opinion leaders to debate the future of spatial biology. Spatial transcriptomics, single cell resolution and tissue preparation were among the key topics raised.

Genome Editing

Genome Editing: Novel Technologies, Tools, and Translation to Therapeutics

Our February Omics discussion group focused on novel genome editing and how new technologies are being used to tackle the challenges of transitioning to therapeutic use.

Digital PCR

Microfluidic Droplet-Based PCR: a Tool to Solve Challenges in Personalised Medicine and Cancer Detection?

In this commentary article, we present Dr Valerie Taly’s insights on the latest research into digital droplet PCR and the potential applications of liquid biopsy in cancer detection.

Spatial Biology

Increase Your Understanding Of Biology With Single Cell RNA Sequencing

Presented by Bastiaan Bijl, Head of Business Development, Single Cell Discoveries & Jens Puschhof, Principle Investigator, German Cancer Research Center

Single Cell Analysis

Characterization of HepaRGŽ cells grown in 2D or 3D culture at single cell level using the cellenCHIP 384-3RNA-Seq Kit

The emergence of single-cell sequencing has opened a new field in analytical biological approaches particularly allowing to uncover cell-to-cell heterogeneity of 3D cellular models and preventing incomplete conclusions drawn from bulk cell populations

Genome Editing

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Spatial Revolution: Harnessing Spatial Technologies In The Clinic For A Healthier Tomorrow

Top R&D Stories of 2023