Biologics - Resources

22/04/24 - Earth Day marks a moment to reflect on the planet's health and our collective efforts to nurture it. To celebrate Earth Day, this article will examine the strides the pharmaceutical and biotechnology industry has made towards fostering sustainable and green practices alongside the challenges.

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Proteins & Antibodies

Rapid Analytical Approach for Biologics Characterization Using Mass Photometry

On-demand webinar featuring Dr Racha Majed, Technical Sales Specialist, Refeyn

Proteins & Antibodies

The Current Landscape of ADC Approvals and Market Trends: Q&A With Mahendra Deonarain, CEO of Antikor Biopharma

While a recent spike in ADC approvals may not last forever, Antikor Biopharma’s Mahendra Deonarain asserts that antibody-drug conjugates are here to stay.

Proteins & Antibodies

Introducing the Development and Clinical Landscape of Bi and Multispecific Antibodies

While bispecific antibodies target two specific entities, multispecific antibodies can target more than two. The use of these engineered antibodies offers the potential for enhanced therapeutic strategies by simultaneously addressing multiple aspects of a disease.

Proteins & Antibodies

Cytokines and Immunocytokines in Therapeutic Approaches

Advancements in cytokine understanding and synthetic immunology enable precise immune modulation, particularly in cancer treatment. However, challenges like short half-lives and side effects impact their wider clinical application.

Proteins & Antibodies

Post-Event Proceedings - Biologics 2023

Concise and insightful summaries of presentations delivered by prominent thought leaders at Biologics 2023

Proteins & Antibodies

Multispecific Antibody Development: Interview with Yue Liu, President and Founder of Ab Therapeutics

Discussing using a computational drug discovery platform for the development of multispecific antibody therapeutics.

Proteins & Antibodies

Handbook for Stem Cell Research

This whitepaper by Sino Biological discusses the different types of stem cells based on their origin and potential, as well as the factors that direct their differentiation toward specific lineages or cell types.

Proteins & Antibodies

FDA Approves Takeda’s Subcutaneous Ulcerative Colitis mAb

The company can now sell their biologic for ulcerative colitis in a subcutaneous form on the US market.

Proteins & Antibodies

Navigating the Pharma R&D Regulatory Landscape 2023

Our ‘Navigating the Regulatory Landscape’ eBook has been designed to provide you with invaluable insights into the intricacies of regulations & policies surrounding the challenges and opportunities of Real-World Data, genome editing, biomedical informatics, manufacturing and many more.

Proteins & Antibodies

Amgen and Synaffix Pen $2 Billion

Amgen and Synaffix's partnership aims to revolutionise cancer treatment by developing highly targeted antibody-drug conjugates (ADCs).

Proteins & Antibodies

F-star and Takeda Collaborate to Pave the Way for Next-Generation Cancer Therapies

F-star Therapeutics and Takeda are partnering to develop next-generation multi-specific antibodies for cancer immunotherapy, building on F-star's advanced platforms.

Proteins & Antibodies

Accelerating time to market through process innovation

On-Demand Workshop presented by Andreas Castan, Strategic Technologies Director at Cytiva, Cauroline Hausner, Business Development Manager, Aseptic Filling at Cytiva, Ola Tuvesson, Chief Technology Officer at NorthX Biologics & Sofie Östemar, Product Manager, Connected & Continuous at Cytiva

Proteins & Antibodies

Xentria and Meitheal Collaborate on Breakthrough Lung Disease Treatment

Xentria and Meitheal partner to develop a breakthrough drug for pulmonary sarcoidosis, aiming to improve patient outcomes.

Proteins & Antibodies

Revolutionising Antibody Engineering: The Groundbreaking Work of Sir Gregory Winter

We take a look at the work of Sir Gregory Winter, and how it has changed the landscape of therapeutic antibody production.

Proteins & Antibodies

Unravelling the Link Between Type 2 Diabetes and Proteins

In honour of this week marking Type 2 Diabetes Prevention Week, we take a look at the intricate link between the disease and proteins.

Proteins & Antibodies

Sony and Astellas Team Up to Create Breakthrough ADC Oncology Platform

Sony and Astellas join forces to develop an ADC platform that leverages Sony's Kiravia Backbone for enhanced drug delivery and stability.

Proteins & Antibodies

App Note: CAR-T: A Promising Cell Therapy for Cancer Treatment

This application note by Sino Biological explores the key steps involved in CAR-T production to provide insights into the challenges that may impede successful CAR-T therapy.

Proteins & Antibodies

Tiny but Mighty Molecular Syringe Developed Using AI

An AI-modified molecular “syringe” harnessed from bacteria could revolutionise protein delivery for gene and cancer therapies.

Proteins & Antibodies

Absolute Biotech: Cancer Research Reagents

Proteins & Antibodies

Absolute Biotech: Recombinant Antibody Services

Proteins & Antibodies

Interview with Andrew Brown, Head of Process Development Sciences at Lonza

Andrew Brown, Head of Process Development Sciences at Lonza, talks about Lonza's approach to process development.

Proteins & Antibodies

How AI is Changing the Game for Protein Design

Researchers at the University of Washington have succeeded in using machine learning to synthesise artificial enzymes which are actually functional in cells.

Proteins & Antibodies

Computational Tools and AI/ML for Antibody Engineering

Opinion leaders from Merck and AbbVie discuss how antibody-based molecular engineering is developing with new AI/ML technologies.

Proteins & Antibodies

POLIVY vs ODAC: Can the Cancer Drug Score Another Indication?

The Oncologic Drugs Advisory Committee are preparing to weigh in on whether the FDA should grant another indication for Roche’s POLIVY.

Proteins & Antibodies

No More Hold-Ups: FDA Lifts Hold on Parkinson’s Drug

The FDA has repealed the hold placed on clinical trials for the Parkinson’s drug IkT-148009, which began in November.

Proteins & Antibodies

FDA Grant Approval for Alzheimer's Drug Leqembi

The US regulators have approved Eisai and Biogen’s Alzheimer’s drug, lecanemab, a “landmark” moment for the disease.

Proteins & Antibodies

Roche Fail to Follow in Eisai’s Footsteps: Alzheimer’s Drug Flunks Phase III Trials

Roche revealed that they will stop all Alzheimer’s trials after anti-amyloid beta antibody gantenerumab fails Phase III trials.

Proteins & Antibodies

Heart-to-Heart or Head-to-Head: Amgen Heart Drug to Challenge Novartis

New data released from Amgen’s phase II study of olpasiran suggests that the drug could fill a niche in the cardiovascular market.

Proteins & Antibodies

AbbVie Ditch Phase II Autoimmune Drug

AbbVie announced that they are dropping the ROR? inverse agonist, marking the end of their collaboration with Inventiva

Proteins & Antibodies

Oxford Global's R&D Key 40 Stories 2022

Download a copy of the R&D Key 40 Stories 2022 eBook today.

Proteins & Antibodies

The STING in Immunotherapy’s Tail

Research from the University of North Carolina into STING agonists provides new insights for immunotherapy cancer treatments.

Proteins & Antibodies

Eisai’s Alzheimer's Drug Offers New Hope

Eisai’s new drug lecanemab has shown small but significant benefits for people with early Alzheimer’s disease.

Proteins & Antibodies

Is Your WASH Causing Inflammation? Protein Complex Linked to Inflammatory Conditions

Research published by the Scripps Research Institute reveals the WASH protein complex as a crucial factor in neutrophil-triggered inflammation.

Proteins & Antibodies

AstraZeneca Suffers Sales Decline for COVID Med Evusheld

A 24 million loss has been reported for the preventative COVID-19 treatment.

Proteins & Antibodies

Market Battle for Rare Disease Treatment

Argenx and AstraZeneca are set to become market rivals in their general myasthenia gravis (gMG) treatments, analysts claim.

Proteins & Antibodies

Widening the Therapeutic Window: Development of Antibody Drug Conjugates for Solid Tumours

Compared to non-solid tumours, solid tumours are more difficult to treat with conventional therapeutic methods. Antibody drug conjugates – biopharmaceutical drugs designed as a targeted therapy for treating cancer – represent a viable treatment alternative.

Proteins & Antibodies

Novartis Withdraws Tislelizumab Submission

Novartis scraps US submission of tislelizumab as a monotherapy for non-small cell lung cancer.

Proteins & Antibodies

Blood Test Predicts Presence of Beta-Amyloid in Brain

A study by the National Institute of Ageing found that a new blood test can accurately predict the presence of beta-amyloid plaques in the brain.

Proteins & Antibodies

Recommended Approval for AbbVie’s Rinvoq Treatment

AbbVie announces official recommended approval of it Rinvoq treatment for adults with active non-radiographic axial spondyloarthritis.

Proteins & Antibodies

Top 3 Biologics News Headlines

Hot off the press, we look at this week’s breaking news stories from the Biologics industry.

Proteins & Antibodies

Delays for New COVID Drugs

Clinical studies testing treatments for severe COVID-19 face major delays due to eligibility issues.

Proteins & Antibodies

Bispecific CAR-T Cell Therapies: Successful Applications in Mouse Tumour Models

Two roadblocks to the successful application of treatments for tumourous tissues are heterogenous antigen expression and antigen loss. Bispecific CAR-T cells, capable of simultaneously binding to two different antigens via heavy chain-only domains, may present a solution.

Proteins & Antibodies

Study Shows ML Optimises Therapeutic Antibodies

Researchers from ETH Zurich demonstrate the promise of deep learning for predicting antigen specificity.

Proteins & Antibodies

Advanced Antibody Engineering: AI, ML, and Computational Tools

Oxford Global’s Discussion Groups provide a focused networking opportunity for a handful of like-minded experts on a monthly basis. Our April Discussion Group addressing ‘Accelerating Antibody Engineering With AI/ML & Advanced Computational Tools and Technologies’ brought together an exclusive panel of key opinion leaders to address the market’s growth and future outlook.

Proteins & Antibodies

What’s Next for Antibody-Based Therapeutic Discovery and Optimisation?

As market leaders in the biologics field, there is no sign of demand for antibody-based therapies slowing down any time soon. With exclusive insights from the CRUK-AstraZeneca Antibody Alliance Laboratory, we look towards the future of antibody discovery and optimisation.

Proteins & Antibodies

Sane in the Membrane: Salipro One-Step Reconstitution of GPCRs and Ion Channels

While membrane proteins are inherently unstable and challenging to work with, Salipro Biotech are focusing on the stabilisation of challenging protein targets for a variety of downstream applications. This Commentary article explores how Salipro’s platform technology enables new opportunities for drug development.

Proteins & Antibodies

Advanced DNA Tools for Engineering Better Chimeric Antigen Receptors

Proteins & Antibodies

AmMagTM SA Plus Automated Protein Purification System

Proteins & Antibodies

AN2 Sensitive Protein Quantification in Whole Blood

Proteins & Antibodies

Bachem: In Vitro Diagnostic Peptides

Proteins & Antibodies

Bionamic Platform Introduction

Proteins & Antibodies

Bio-Techne Product Portfolio Overview

Proteins & Antibodies

Bio-Techne: Genome Engineering for Cell Therapy Manufacturing

Proteins & Antibodies

Bio-Techne: Maurice

Proteins & Antibodies

Bio-Techne's Custom Reagents and Contract Services

Proteins & Antibodies

Bio-Techne's Ella: Your Immunoassay Problem Solver

Proteins & Antibodies

Bio-Techne's Jess: Your Complete Protein Analysis Solution

Proteins & Antibodies

Extracellular Vesicle Quantification in Complex Matrices

Proteins & Antibodies

High Sensitivity Assay Development on the LSA®

Proteins & Antibodies

High Throughput Gene-to-Antibody Production Services

Proteins & Antibodies

High Throughput SPR Kinetics

Proteins & Antibodies

Hyperimmune Library

Proteins & Antibodies

InstaDeep Promoted to NVIDIA Elite Service Delivery Partner

Proteins & Antibodies

Label-Free Protein Quantification in Bioproduction Samples

Proteins & Antibodies

Monitoring Immune Response to SARS-CoV-2

Proteins & Antibodies

NiHC200M Biosensor Kinetic Assays on the Carterra® LSA®

Proteins & Antibodies

PSILO® - Protein Structure Database and Visualization System

Proteins & Antibodies

Sensitive Protein Quantification in Crude Serum Samples: Comparison of FO-SPR and ELISA

Proteins & Antibodies

Solutions for the Whole Life Sciences Laboratory

Proteins & Antibodies

Speeding up T-Cell Receptor Discovery for Adoptive Cell Therapy

Proteins & Antibodies

Twist AI Hypermutated scFv Library

Proteins & Antibodies

Twist Ancestral scFv Library

Proteins & Antibodies

Twist Carbohydrate scFv Library

Proteins & Antibodies

Twist Combinatorial Assembly

Proteins & Antibodies

Twist Ion Channel scFv Library

Proteins & Antibodies

Twist Minotaur scFv Library

Proteins & Antibodies

Twist Structural scFv Library

Proteins & Antibodies

ABclonal Molecular Biology Reagents

Proteins & Antibodies

ABclonal Product Introduction

Proteins & Antibodies

Ablexis and AlivaMab Discovery Services

Proteins & Antibodies

AmMag Protein A Magnetic Beads for Rapid Antibody Purification

Proteins & Antibodies

Biologics by Design

Proteins & Antibodies

Biologics... Changing Treatment, Saving Lives

Proteins & Antibodies

Bio-Techne: Bioprocess Workflow Solutions

Proteins & Antibodies

Custom Services of ABclonal

Proteins & Antibodies

Detecting Partial Unfolding of Hen Egg White Lysozyme in 2 M Guanidine Hydrochloride Solution using Microfluidic Modulation Spectroscopy (MMS)

Proteins & Antibodies

Introduction of ABclonal Molecular Enzyme Products

Proteins & Antibodies

Microfluidic Modulation Spectroscopy as a Non-Destructive Structural Characterisation Technique

Proteins & Antibodies

MOE - The Integrated Computational Platform

Proteins & Antibodies

Multi-Parameter Epitope-Centric Data Used to Elucidate Mechanisms of Action of Antibodies

Proteins & Antibodies

SARS-CoV-2 Research Reagents

Proteins & Antibodies

Secondary Structure Analysis of NIST Monoclonal Antibody Reference Material 8671 by Microfluidic Modulation Spectroscopy

Proteins & Antibodies

The Molecular Operating Environment: Biologics Design and Protein Engineering

Proteins & Antibodies

T Cell Engagement and Redirection – Strategies, Methods, and T Cell Design

Oxford Global’s Discussion Groups provide a focused networking opportunity for a handful of like-minded experts on a monthly basis. Our February Discussion Group addressing ‘T Cell Engagement and Redirection – Strategies, Methods, and T Cell Design’ was a tremendous success. The discussion brought together an exclusive panel of key opinion leaders to address the key factors behind the market’s growth, its priorities, future outlook, and challenges.

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