While both allogeneic and autologous cell therapies have seen a recent boom, the two approaches differ in terms of scale and customisation.

Novel applications of stem cells drive personalized medicine, tailoring treatments to each patient's unique profile. Explore groundbreaking applications for more effective, individualized therapies.

An animal model study suggests that cells produced by breast cancer preferentially metastasize to the spine over other bones in the body, with key proteins identified as affecting spinal tropism.

Transient-native-transient reprogramming enables researchers to sidestep the differentiation quirks which can complicate the use of induced pluripotent stem cells by resetting their epigenetic memory.

A study from Duke University found that a lipid present in breast milk promotes a process leading to the generation of new brain cells, which could potentially aid in the repair of damaged white matter in infants with cerebral palsy.

Traditionally, cell fate and differentiation were considered to be a one-way journey. However, recent research using animal models like zebrafish has challenged this perspective.

With evidence suggesting that microgravity conditions may be best for growing and developing pluripotent stem cells, a team of astronauts aboard the International Space Station are set to test this hypothesis.

Over the past 50 years, rare disease research has paved the way for medical breakthroughs such as allogeneic stem cell transplantation. Other focuses have included the identification of potential drug targets by analysing cellular and molecular pathways.

Can advanced analytical processing and real-time data monitoring conquer the complexity of Bio-pharmaceutical manufacturing? We ask Udayanath Aich, Director at Bristol Myers Squibb.

How can combinatorial screening of diverse variables in process development optimise cell and gene therapies? Marina Tarunina, Research Director at Plasticell, investigates.

In this Commentary article, we explore how reductions in testing complexity can improve access to hematopoietic stem cell therapies for patients with blood disorders. The provision of safe, effective therapies will help to ameliorate the worst impacts of these disorders for patients and afford them a better quality of life.

Regenerative medicine is a highly promising branch of pharmacology. With the growing demand for stem cell therapies, the need for streamlined manufacturing is more critical than ever. We sat down with senior representatives from Procella Therapeutics, the University of Reading, and Newcastle University to learn more about the future of stem cell production.

Dr Darius Widera shows us three case studies on 3D stem cell cultivation using fibrin, nanofibrillar cellulose, and hybrid scaffolds