Biologics - Resources

22/04/24 - Earth Day marks a moment to reflect on the planet's health and our collective efforts to nurture it. To celebrate Earth Day, this article will examine the strides the pharmaceutical and biotechnology industry has made towards fostering sustainable and green practices alongside the challenges.

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Oligonucleotides

Japanese Team Successfully Skip Abnormal Gene In Vitro With Antisense Oligonucleotide for BPAN

Rare disease BPAN currently has no treatment options, this new research investigates whether antisense oligonucleotide therapies could be the answer to address this unmet need.

Oligonucleotides

Oligo Sequencing Technologies - What Methods and Techniques Are Utilized in the Pharmaceutical Industry?

Oligo sequencing revolutionizes biologics research, ensuring accurate analysis of oligonucleotides. Biologics by Oxford Global explores methods, safety, sustainability, and future trends. Despite challenges, advancements promise exciting opportunities for scientific discovery.

Oligonucleotides

Innovation at the Crossroads: Oligonucleotide Therapeutics and the Evolution of Drug Design

Can oligonucleotide therapeutics shape the future of healthcare? We journey through AI frontiers, sustainable synthesis, and regulatory challenges.

Oligonucleotides

Sustainability in Pharmaceutical Manufacture and Healthcare Provision

How do things stand with sustainability in pharmaceutical manufacture at present? What are some members of the industry doing to reduce their carbon footprint?

Oligonucleotides

New Approach to Oligo-Peptide Synthesis from Novo and Aarhus University

The collaboration could unlock the more cost-effective synthesis of oligonucleotide-peptide conjugates.

Oligonucleotides

How Do Regulatory Considerations Impact the Clinical Development of Oligonucleotide Therapies?

What are the regulatory considerations that need to be made in the clinic for oligonucleotide therapies? What's the existing guidance for this emerging modality?

Oligonucleotides

Revolutionizing Biologics: Unveiling the Challenges and Innovations in Large-Scale Oligonucleotide Synthesis

Oligonucleotides

Assessment of Long IVT mRNA Fragments with the Aligent Fragment Analyzer Systems

Oligonucleotides

Early Formulation Screening with Merck

Oligonucleotides

Early-Stage Development of LNP Formulations

Oligonucleotides

Friedrich Miescher: The Pioneer of Nucleic Acid Discovery

As medical research that is founded on nucleic acids continues to progress, we take a step back to look at the man who first discovered nucleic acids.

Oligonucleotides

GMP Manufacturing of LNP Formulations

Oligonucleotides

Lipids for Pharmaceutical Applications

Oligonucleotides

mRNA CDMO Services to Accelerate your mRNA Program

Oligonucleotides

Oligonucleotide Purification Solutions

Oligonucleotides

Rapid Analysis of mRNA 5' Capping

Oligonucleotides

Solid Phase Oligonucleotide Synthesis

Oligonucleotides

The Growing Potential for Antisense Oligonucleotide Therapy

Antisense oligonucleotides hold major promise in future patient treatment approaches. Through targeting RNA to regulate protein expression, they can help to address diseases at their source and advance therapeutic outcomes.

Oligonucleotides

Targeted Delivery with FORCE: Novel Approaches in Oligo Therapeutics

How are oligo therapeutics revolutionising genetic disease treatments through precise targeting and transformative therapies? In this article, we explore how they provide precise gene expression interference for untreatable conditions by directly targeting disease-associated proteins and genetic mutations.

Oligonucleotides

Transforming Oligonucleotide Manufacturing: A Transformative UK Collaboration

A new collaboration from the Medicines Manufacturing Innovation Centre is looking to change the face of oligonucleotide development.

Oligonucleotides

Refractive Index Paves the Way to Greener Peptide and Oligonucleotide Synthesis

John Lopez of Novartis discusses the more sustainable possibilities refractive index monitoring offers in SPPS and SPOS.

Oligonucleotides

Agilent: Oligonucleotide Purification Solutions

Oligonucleotides

Twist Bioscience: Oligo Pools

Oligonucleotides

The Complex Case of Antisense Oligonucleotides

We gain a glimpse into what the landscape of antisense oligonucleotides looks like today, from computational representations to protein purification.

Oligonucleotides

Sciex Molecular Profiler Software

Oligonucleotides

Sciex Zeno Trap

Oligonucleotides

Sustainable Synthesis of Therapeutic Oligonucleotides

Oxford Global’s Discussion Groups provide a focused networking opportunity for a handful of like-minded experts on a monthly basis. Our March Discussion Group addressing ‘Sustainable Synthesis of Therapeutic Oligonucleotides’ brought together an exclusive panel of key opinion leaders to address the market’s growth and future outlook.

Oligonucleotides

Optimising Oligonucleotide Therapies: Efficacy, Targetability, and Precision Medicine

With efficacy, safety, and targetability being the top three challenges facing the nucleotide-based therapeutic industry today, will oligo-based therapies fulfil their potential as a clinical modality?

Oligonucleotides

Oligonucleotide Chemistry & Therapeutics Symposium: Market Trends and Industry Challenges

The first of its kind, the Oligonucleotides: Chemistry & Therapeutics Symposium was a hit. We sat down with an advisory group of leading industry experts to hear their thoughts on the future of the Oligonucleotide drug industry as well as some of its key market trends and challenges.

Oligonucleotides

Characterisation of Therapeutic Oligonucleotides in Early Drug Discovery

Oligonucleotides are fast becoming a globally recognised form of therapeutic treatment. But how easy is it to analyse them? Director of AstraZeneca, Tomas Leek takes us through the analytic challenges of the early-stage oligonucleotide characterisation.

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