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 The latest in cell & gene research, from advanced therapies through to the latest developments in cell & gene research, therapies & manufacturing

Top R&D Stories of 2023

Through captivating articles, insight pieces, and spotlight interviews, we delve into the remarkable innovations, breakthroughs, and scientific marvels that have defined the landscape of research over the past year.
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Cell & Gene Therapy Manufacturing

Proactive Approaches to Cell Culture Media and Process Control Strategies

Merck invests $25 million in a Kansas cell culture media plant, aiming to meet rising demand for advanced therapeutics while aligning with sustainability goals.
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Cell & Gene Therapy Manufacturing

In Conversation With… Sophie Mountcastle, Network Manager, Innovation Hubs for Gene Therapies

Here, we discuss the crucial role of a collaborative network for gene therapy development across the UK and some of the successes seen to date.
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Cell & Gene Therapy Manufacturing

AppNote CBM Highthroughput AAV Viral Titering using Nano-Plate Based Digital PCR

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Cell & Gene Therapy Manufacturing

Automated Isolation of Cells into Low Volumes for scWGA

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Cell & Gene Therapy Manufacturing

Automated and Gentle Isolation of Single Cells for Efficient Cloning of hiPSCs

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Cell & Gene Therapy Manufacturing

Cellular Insights Guide Discoveries

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Cell & Gene Therapy Manufacturing

CERO - A Benchtop Incubator and Bioreactor

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Cell & Gene Therapy Manufacturing

Cytokine Guide for Researchers

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Cell & Gene Therapy Manufacturing

Cytokine Master Booklet Compact

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Cell & Gene Therapy Manufacturing

Comprehensive CAR-T Therapy Development Solutions

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Cell & Gene Therapy Manufacturing

Custom Services to Advance Drug Discovery

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Cell & Gene Therapy Manufacturing

Digital PCR Applications and Gene Expression

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Cell & Gene Therapy Manufacturing

Digital PCR for Sensitive Research Applications

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Cell & Gene Therapy Manufacturing

Exploring the Effects of Insulin on Viral Vectors Production in HEK293 Cells

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Cell & Gene Therapy Manufacturing

Handling and Delivering Single Cells

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Cell & Gene Therapy Manufacturing

Improve Your Upstream Manufacturing with Recombinant Insulin

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Cell & Gene Therapy Manufacturing

Identifying Highly Potent TNF-a Secretors

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Cell & Gene Therapy Manufacturing

Immune Cell-Mediated Killing of A549 Cancer Target Cells in Real-Time

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Cell & Gene Therapy Manufacturing

How Current and New Technologies can Overcome Challenges in Adherent Scale-Up

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Cell & Gene Therapy Manufacturing

Monitoring Cell Attachment and Tight Junctions in the Same Assay

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Cell & Gene Therapy Manufacturing

Next Level Live-Cell Kinetic and Phenotypic Assays

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Cell & Gene Therapy Manufacturing

Optimising CHO-K1 Fed-Batch Cell Culture Mediums for mAb Production

The Chinese Hamster Ovary (CHO) cell line is widely used to produce recombinant proteins due to its high growing capacity and productivity.
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Cell & Gene Therapy Manufacturing

Orbital Shaken Benchtop Bioreactor for Single-Use Bags

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Cell & Gene Therapy Manufacturing

Recombinant Protein and Antibody Production

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Cell & Gene Therapy Manufacturing

Reagents for Oncology Research

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Cell & Gene Therapy Manufacturing

Reagents for Drug Target Research

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Cell & Gene Therapy Manufacturing

Quantifying Individual Cells That Secrete Cytokines

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Cell & Gene Therapy Manufacturing

Rapidly Identifying Active Natural Killer Cells

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Cell & Gene Therapy Manufacturing

Rapid and High Throughput Recombinant Antibody Production

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Cell & Gene Therapy Manufacturing

Revealing and Retrieving Highly Potent IFN-y Secretors

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Cell & Gene Therapy Manufacturing

Scaling Adherent Cell Culture with Corning HYPER Technology

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Cell & Gene Therapy Manufacturing

Shorten the Path to Your Next Life-Changing Breakthrough

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Cell & Gene Therapy Manufacturing

Seeding, Expanding, and Harvesting Stem Cells

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Cell & Gene Therapy Manufacturing

The Next Level of Live-Cell Analytics

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Cell & Gene Therapy Manufacturing

Toolkits for CAR-NK Therapy Targets

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Cell & Gene Therapy Manufacturing

The Perfect Solution for Shaken Cultivation Processes

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Cell & Gene Therapy Manufacturing

Unprecedented Flexibility for HTS Automated Patch Clamp

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Cell & Gene Therapy Manufacturing

Innovative Financial Strategies in Gene Therapy: A Shift Towards Sustainable Access

Discover the key strategies and financial nuances of gene therapy like outcome-driven contracts, payment plans, and shared financial agreements
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Cell & Gene Therapy Manufacturing

Sustainability in Cell Therapy Manufacture: Improving Process Efficiency for Cell Line Development

Improving process efficiency is a key approach to factor in when looking at how cell therapy manufacture can be made more sustainable.
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Cell & Gene Therapy Manufacturing

CAR T-REX Aims to Bolster Anti-Tumoural Immune Response

An international European consortium has received a €2.7m grant to improve the safety and effectiveness of CAR-T cell therapies for solid tumours. If successful, the grant could massively improve treatment outcomes for patients.
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Cell & Gene Therapy Manufacturing

Crossing the Pond: Key Considerations for Stateside Biotechs Looking to the UK and Europe

Among the challenges faced by US biotechs looking at setting up in Europe, regulatory and cultural differences are chief among them. However, the strong tradition of scientific research and high standard of medical care across the Atlantic makes it worth the effort.
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Cell & Gene Therapy Manufacturing

Healthcare Data Platforms: Expert Tips on Integrating Digitalisation with Cell and Gene Manufacturing

Developers looking to integrate digitalisation approaches into their pipeline should ensure that they choose a sensible architecture, rather than simply automating for the sake of it.
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Cell & Gene Therapy Manufacturing

Metabolic Modelling and Machine Learning Technologies in Cell and Gene Manufacturing

Integrating PAT into metabolic modelling can help optimise the product obtained from cell cultures, augmenting the manufacturing process.
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Cell & Gene Therapy Manufacturing

Cell and Gene Manufacturing Approaches and Winning Strategies for Commercialisation and Scale-Up

With a host of factors to consider in cell and gene manufacture, upscaling is still no small task. However, as industry experience accumulates and new technologies arrive on the market, there are an increasing number of options for developers looking to get their therapeutic on the road to the clinic.
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Cell & Gene Therapy Manufacturing

AI in Gene Therapy: How Could Machine Learning Approaches Reshape Therapeutic Development?

As more developers bring their cell and gene therapy products to industry regulators, the need to drive cost and process efficiencies is on track to keep growing. Across the board, AI and machine learning approaches have the potential to streamline many aspects of development.
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Cell & Gene Therapy Manufacturing

Industry Insights Into the FDA's Plans for Revised Gene Therapy Approval Approaches

Some additional measures announced include the launch of the Cell and Gene Therapy Access Model, as well as the interpolation of RWE into trials and a potential move away from animal models in validating treatment efficacy.
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Cell & Gene Therapy Manufacturing

Q &A with Shilpi Rajoria

An interview Shilpi Rajoria, Director QC Analytical Testing at Bristol Myers Squibb.
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Cell & Gene Therapy Manufacturing

Overcoming the Challenges in Cell Therapy Manufacturing

Udayanath Aich, Director at Bristol Myers Squibb, leads a Discussion Group on leveraging advanced technologies and biologics to mitigate challenges.
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Cell & Gene Therapy Manufacturing

Looking into the Crystal Ball: The Future of Disruptive Cell and Gene Therapy Manufacturing

What will the future hold for autologous cell and gene therapy manufacturing? Tigen Pharma SA, share their predictions on the prospect of disruptive innovation for the industry.
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Cell & Gene Therapy Manufacturing

AAV Manufacturing Using Osmolality

New Data from the Cell and Gene Therapy Catapult shows improved yield, quality, and process efficiency for AAV manufacturing using osmolality.
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Cell & Gene Therapy Manufacturing

In Conversation With...Ruth Faram, HigherSteaks

Dr. Faram is co-founder and Chief Scientific Officer at HigherSteaks, where she leads the company strategy and research focus for the Stem Cell, Bioprocess, Differentiation and Biomaterial teams.
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Cell & Gene Therapy Manufacturing

In Conversation With Jenny Prange, Head of GMP Production, Chief Scientific Officer and Co-Founder of Muvon Therapeutics

The present and the future, key insights into the cell and gene therapy manufacturing space
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Cell & Gene Therapy Manufacturing

Developing Meaningful Assays: Balancing Biological Significance and QC-Compatibility

Katrina Adlerz, Scientist at The University of Texas MD Anderson Cancer Center presents on developing meaningful biologic assays at the Cell Therapy Analytics Symposium 2022.
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Cell & Gene Therapy Manufacturing

Gene Therapy Manufacturing

June's Discussion Group welcomed a panel of industry experts to debate manufacturing and standardisation challenges for the commercialisation of cell and gene therapies.
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Cell & Gene Therapy Manufacturing

Biocair Case Study: Best in Class Performance

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Cell & Gene Therapy Manufacturing

Bio-Techne: Genome Engineering Services for Cell Therapy Manufacturing

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Cell & Gene Therapy Manufacturing

Bio-Techne: GMP ProDotsâ„¢ Proteins, a User Guide

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Cell & Gene Therapy Manufacturing

Bio-Techne: Product Portfolio Overview

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Cell & Gene Therapy Manufacturing

Bio-Techne's Ella: Your Immunoassay Problem Solver

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Cell & Gene Therapy Manufacturing

Bio-Techne: Cell and Gene Therapy Manufacturing Solutions

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Cell & Gene Therapy Manufacturing

Bio-Techne: Changing the Way Scientists Analyse Proteins

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Cell & Gene Therapy Manufacturing

Streamlining Stem Cell Manufacturing

Oxford Global's Discussion Groups provide a focused networking opportunity for a handful of like-minded experts on a monthly basis. Our January Discussion Group addressing ‘Streamlining Stem Cell Manufacturing' was a tremendous success. The discussion brought together an exclusive panel of key opinion leaders to address the key factors behind the market's growth, its priorities, future outlook, and challenges.
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