Resources
The latest in biomarkers research, from development and diagnostics to precision medicine
Through captivating articles, insight pieces, and spotlight interviews, we delve into the remarkable innovations, breakthroughs, and scientific marvels that have defined the landscape of research over the past year.
Diagnostics
Blood Test for Alzheimer's Granted Breakthrough Device Status by FDA
A blood test for the phosphorylated protein pTau-217 could be a critical step towards early diagnosis and screening of Alzheimer's disease.
Diagnostics
Early Diagnostic Blood Biomarker for Dementia Identified Using Proteomics
The team hopes to develop the biomarker into a test that could be used in GP surgeries. Early prediction of dementia could be a gamechanger for new Alzheimer's therapies.
Diagnostics
Investigating Biases in Diagnostics and Biomarkers: Three Case Studies
In the quest to improve diagnostics, new technologies are key, but so is overcoming entrenched bias.
Diagnostics
Machine Learning Metabolomics Approach Used to Diagnose Ovarian Cancer
Researchers have used an artificial intelligence model to analyse the metabolites of patients with or without ovarian cancer and have reported shocking accuracy of diagnosis.
Diagnostics
Using Biosensors for Biomarker Identification and Validation in Lung Cancer
Advancements in biosensors, notably graphene-based ones, show promise in swiftly identifying elusive lung cancer biomarkers, potentially revolutionising early diagnosis.
Diagnostics
Dynamic Biomarkers for Deep Immune Phenotyping in Autoimmune Disease
On-Demand Webinar featuring Dr Mo Jain, Founder & CEO of Sapient & Dr Tanya Nguyen, Head of Scientific Operations of Sapient
Diagnostics
A Wearable Ultrasound Patch for the Home Detection of Breast Cancer
Researchers from MIT have developed a wearable ultrasound patch that can image breast tissue, potentially facilitating the home detection of breast cancer. The patch can be attached a bra, and shows promise in detecting small cysts.
Diagnostics
Plasma Biomarkers Show Promise in CNS Trials for Alzheimer's Disease
Proteins in the brain and plasma of individuals with sporadic Alzheimer’s disease are altered, supporting the hypothesis that plasma biomarkers have utility in predicting early onset in cognitively unimpaired populations.
Diagnostics
ddPCR Approaches for Biomarker Detection and Analysis
The high sensitivity and specificity of ddPCR assays makes the approach well-suited for screening diseases and diagnosing cancer subtypes. Here, we explore some of the ways in which medical researchers are using the technology to pioneer detection of circulating biomarkers for liquid biopsies.
Diagnostics
Blood-Based Biomarkers and Liquid Biopsies in Cancer Treatment: Precision Oncology Approaches and Strategies
Blood is a rich source for biomarker development, and CTCs are increasingly proving themselves to be valuable in cancer prognosis and treatment prediction.
Diagnostics
High Sensitivity Phenotyping of Extracellular Vesicles by Customized, Single-Molecule Assays
On-Demand Webinar featuring Marina Cretich, Senior Researcher of the National Research Council of Italy at SCITEC-CNR
Diagnostics
Emergency Use Authorization Issued by FDA for Mpox Virus DNA Test
EUAs exist under FDA regulation to improve the availability of medical countermeasures, such as vaccines and diagnostic tests, during public health emergencies. With future pandemics a tangible possibility, further EUAs for other PCR tests and vaccines are all but certain.
Diagnostics
Study Reveals Altered Spontaneous Brain Activity in People with Down Syndrome
A new study has revealed that using functional magnetic resonance techniques shows the differences in the spontaneous activity of the brain in people with Down syndrome compared to the general population.
Diagnostics
The Ethical Issues of Pre-Emptive Dementia Diagnosis
If you were at risk of developing Alzheimer’s disease, would you want to know?
Diagnostics
Low-Cost Method for Cancer Testing
The Heatrich-BS assay is a novel low-cost sequencing method for low-cost cancer testing.
Diagnostics
Functional Cure Biomarker for Hepatitis B Virus
Study suggests the haplotype number for hepatitis B virus could act as a predictive biomarker for functional cure during antiviral therapies.
Diagnostics
Can Protein Shapes Indicate Parkinson's Disease?
The first ever potential biomarker for Parkinson’s disease has been discovered.
Diagnostics
Urinary Biomarker Detects Early Onset of Alzheimer’s Disease
Discovery of a new sensitive urinary biomarker could pave the way for cost-effective and large-scale screening of neurodegenerative disease.
Diagnostics
Diagnostic Biomarkers Discovered for Lyme Disease
New hope raised for the early detection and treatment of the tick-borne illness.
Diagnostics
Predicting Heart Disease Risk with ‘Good’ Cholesterol: Is it Still Viable?
A new study analysing the cholesterol levels of black adults challenges traditional perceptions of its role in predicting heart disease risk.
Diagnostics
Predicting Preeclampsia Risk with Placental Proteins
A new study by Cedars-Sinai could identify protein biomarkers for preeclampsia.
Diagnostics
Genetic Variants Linked to Dyslexia
A new study from the University of Edinburgh has identified potential gene indications associated with dyslexia.
Diagnostics
Thirdhand Smoke Triggers Skin Disease
New research suggests acute exposure to thirdhand smoke elevates biomarkers associated with skin diseases.
Diagnostics
Towards Improved Biomarker Analysis and Validation
Key opinion leaders talk understanding the scientific and regulatory considerations for the qualification of biomarkers.
Diagnostics
New Gene Target Discovered for Aggressive Lung Cancer
Scientists at Northwestern Medicine propose a potential biomarker for identifying small-cell lung cancer.
Diagnostics
Human Stem Cell Models of Neurodegeneration: Exploiting In Vitro Phenotypes to Support Drug Delivery
In this Commentary article, we investigate the applications of human stem cell modelling for identifying the ways in which neurodegenerative diseases such as Alzheimer's and Parkinson's affect the brain.
Diagnostics
Disruptive Innovation in Diagnostics
Data management for diagnostic devices is fast becoming a vital concern of the biomarkers industry. With the increased prevalence of ML and AI, this article interviews key opinion leaders from Nottingham Trent University, Apis Assay Technologies, and UCB about the future perspectives of diagnostic innovation and regulation.
Diagnostics
Non-invasive Early Disease Detection and Precision Medicine Using Breath Biomarkers
Breath is the ideal biomarker matrix for the future of diagnostics. Sample collection is non-invasive, painless and easy to perform, and breath is a rich source of potential biomarkers. Potential applications for breath tests include disease detection, phenotyping, progression and treatment monitoring, and complementary diagnostics. Discover the benefits and capabilities of breath testing, and start researching breath biomarkers with Breath Biopsy®.
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