June 2022

Discussion Group Leader: Grover Amit – Associate Principal Scientist (AstraZeneca)

Discussion Topics:

• What are we learning about the tumour microenvironment?
• Transability and real world results
• Identification & challenges of different cell types
• Protein level analysis
• Preservation techniques
• Tumour metabolism 
• Organoids and the challenge of losing immune context
• Repurposing immune cells in tumour contexts – from defence to attack

June 2022

Discussion Group Leaders:
Patrick Descombes – Senior Expert Genomics & Genomics Group Leader (Nestle Research)
Ed Oakeley – Associate Director of Genomics (Novartis)
Massimo Delledonne – Professor (University of Verona)

Discussion Group Topics:

• DNA methylation with new PacBio pipeline
• Isoforms characterization by long reads
• Reference genomes (human, plants, bacteria)
• Pan genome concept and analysis
• Metagenomics analysis

April 2022

Discussion Group Leader: 

Yann Abraham – Senior Principal Scientist (Janssen)

Discussion Topics:

• The Potential of Single Cell Proteomics
• Complementarity with Transcriptomics
• Targeted versus Unbiased Proteomics
• Bridging the gaps with CITEseq
• Immuno-Oncology
• Phenotypes, Transcriptomes, and Proteomes
• Connecting Academia and Pharma Companies
• Leveraging Single Cell Atlas’ in Real World Applications

Pieter van der Velden – Senior Researcher at Leiden University Medical Centre · Department of Ophthalmology

Presentation:

Advanced digital PCR analysis

Discussion Topics: 

• DNA Methylation Quantification in health and disease?
• T cell counting and IPDA in HIV control viral load and – cell quantification
• DNA-based deconvolution of the tumour microenvironment

February 2022

Discussion Group Leader: Raffaele Adolfo Calogero (Associate Professor, Turin University)

Presentation: 

• Is spatial biology feasible given the actual available technologies?
  
  

Panel Discussion:

• Which kind of single cell omics must be available as spatial application?
• Multi-modality in spatial applications is needed?
• What can be improved in spatial transcriptomics?
• Which kind of computing applications are needed in the field of spatial biology?
• Is 3D spatial biology possible?

February 2022

Genome editing is an exciting and rapidly changing field.  Join this month’s discussion group to meet key pioneers in the field and explore the latest innovations and latest ideas for overcoming scientific and market challenges. 

Topics

• Application for Therapy
• Delivery – Alternative delivery systems
• Safety – Preclinical safety packages and regulatory approval
• Novel Tools
• Preexisting immunity to CAS9 Enzymes
• Ex-Vivo Genome Editing
• Diagnostics

December 2021

Advances in next-generation sequencing allowed us to generate vast amounts of multi-omics data for various applications. This process, however, poses many challenges for researchers to overcome. Join our discussion group exploring how we can streamline some of the key issues posed by data analysis and storage access as well as moving towards the integration of multi omic data & datasets. Attended by bioinformatics leaders in the field, this one-of-a-kind session will allow you to knowledge-share, network and debate areas that really matter to you.

Panel Discussion:

• Data analysis – challenges, platforms & technologies 

• Data storage access 

• Multi omics data integration 

• Multi omic datasets 

Discussion Group Leaders:  

• Hywel Williams, Senior Lecturer in Bioinformatics, Cardiff University
• Raffaele Calogero, Professor, University of Torino