Discover advanced monitoring, environmental controls, mathematical models, PAT tools, and sensor technologies shaping the future of biopharmaceuticals

Upstream Bioprocess Development.

Hemant Dhamne, Head of Process Development of Gene Therapy at King's College London, discusses the process of viral vector production, the current and future manufacturing technologies, and challenges in the field.

Tuhina Bhattacharya, Associate Director of CMC Biologics at Corbus Pharmaceuticals, leads a Discussion Group on the future of downstream bioprocessing technologies.

Amir Reza Goudarzi, former Engineering Head of UCB in Brussels, leads a discussion on ‘Upstream Bioprocessing.'

Key opinion leaders from Novartis, Achilles Therapeutics, and AbbVie divulge their views on what's next for upstream bioprocessing.

This Commentary article investigates the potential applications of digital twins in refining the developmental timeline for drug substance development. Capturing and conserving the understanding from ongoing processes allows researchers to learn more about the intricacies of the developmental process more rapidly.