Virtual Symposium: Targeted Protein Degradation & PROTAC

Day One: 16 February

• Interrogating Protein Structures With Molecular Glues And Developing New Therapeutic Modalities
• Developing New Therapeutic Modalities For Targeting The Protein Degradation Machinery
• Monovalent Degraders/Molecular Glue Degraders
• Design of Degraders and PROTAC In Cellular Development
• Bifunction Small Molecules For Degrading Extracellular Proteins
• Interrogating Protein Structures With Small Molecules, Molecular Glues And PROTACS
• Protein Degradation Workshop – Development of Degraders From A Medicinal Chemistry Perspective
• E3 Ligase Recruiter To Ubiquitinate And Mark Proteins Of Interest For Proteasomal Degradation
• Reimagining Druggability using Chemoproteomic Platforms

Day Two: 17 February

• Panel Discussion: Protein Degradation – Strategies Beyond The Proof Of Concept Molecules
• PROTAC- Receptor Kinase Targets & PKPD
• Protein Degradation For Developing New Targets in Oncology
• The Impact Of Mass Spectrometry-Based Proteomics For Targeted Protein Degradation
• Enabling DNA Encoded Libraries as a High Content Discovery Tool for Protein Degradation Molecules
• Optical Control of Protein Degradation
• Delivering Clinical Candidate Drugs Using Degraders
• TRK Degraders for Oncology – New Modality For The Treatment Of Cancer
• Protein Degradation Seminar Workshop -Translation to the Clinic
• Optimize PK/PD properties of next generation protein degraders for applications in oncology and beyond
• Translation Of Protein Degradation Probes Into Safe, Effective Therapeutics