Prof Dr Elizabeth de Lange has been trained as a chemist, with specialization in Biophysical Chemistry (Groningen University, Groningen, The Netherlands). She obtained her PhD in Pharmacology (Leiden- Academic Center for Drug Research (LACDR), Leiden University, The Netherlands), and is currently professor in Predictive Pharmacology at the Research Division of Systems Biomedicine and Pharmacology of the LACDR. Her scientific focus is on interspecies extrapolation and prediction of human drug effects by development of translational mathematical models on the basis of (pre)clinical data. She is an internationally recognized expert on the combination of highly advanced in vivo experiments (i.e. microdialysis in the brain), analytical techniques, and mathematical and computational models (Mastermind research Approach). In 2013, she received the prestigious AAPS Fellow Award from the American Association of Pharmaceutical Scientists, the largest organisation in her field.