In-Depth

The In-Depth page consists of Insight Articles, Commentaries, C-level Q&As, Discussion Group Reports, and Survey Reports.

Discussion Group Report
This month’s discussion was led by Pieter van der Velden. Topics included improving multiplex assays, T-Cell quantification and DNA methylation.
By Oliver Picken |
05 May 2022
Digital PCR
Insight Article
Single-cell proteomics has developed quickly, despite being a relatively new field. NanoPOTS and FACS are being used to improve proteome coverage and minimise sample size.
By Oliver Picken |
05 May 2022
Single Cell Analysis
Commentary
At NGO US: In-Person 2022, Carlos Cruchaga of the Washington School of Medicine presents on using QTL and GWAS data to unlock the future of therapeutic treatment for neurodegenerative disease.
By Tia Byer |
30 April 2022
NGS & Clinical Diagnostics
Insight Article
Explore the history of PCR and how digital droplet PCR is being used to further understanding of Sars-Cov2 severity.
By Oliver Picken |
25 April 2022
Digital PCR
Insight Article
With the development of single-cell RNA sequencing, it became possible to measure transcriptomes at a single-cell resolution. Is spatial transcriptomics the next step on the journey of understanding human biology?
By Oliver Picken |
21 April 2022
Spatial Biology
Discussion Group Report
Our February discussion group bought together more than 40 key opinion leaders to debate the future of spatial biology. Spatial transcriptomics, single cell resolution and tissue preparation were among the key topics raised.
By Oliver Picken |
17 March 2022
Spatial Biology
Discussion Group Report
Our February Omics discussion group focused on novel genome editing and how new technologies are being used to tackle the challenges of transitioning to therapeutic use.
By Oliver Picken |
11 March 2022
Genome Editing
Commentary
In this commentary article, we present Dr Valerie Taly’s insights on the latest research into digital droplet PCR and the potential applications of liquid biopsy in cancer detection.
By Ben Norris |
11 March 2022
Digital PCR
Insight Article
Due to the heterogeneity seen in both eukaryotic and prokaryotic cell populations, single cell analysis opens up many new possibilities.
By Oliver Picken |
14 February 2022
Single Cell Analysis
Insight Article
Spatial omics is changing how we think about biology, giving us an unprecedented view into single cells and tissues.
By Oliver Picken |
09 February 2022
Spatial Biology
Commentary
When gene therapy goes wrong, it can have severe consequences. Dr Giandomenico Turchiano tells us how he can use ddPCR to catch those mistakes
By Tom Cohen |
31 January 2022
Gene Therapy Development
Commentary
The applications of NGS are swiftly expanding, and new methods for data storage, analysis, and visualisation are needed. However, the complexity of sample processing for NGS has created problems in managing, analysing, and storing the datasets. 
By Oliver Picken |
03 November 2021
NGS & Clinical Diagnostics
Insight Article
Leading experts discuss Next Generation Sequencing; how it is developing, its current and future applications, and what challenges face it today and tomorrow.
24 February 2020
NextGen Omics Series, NGS & Clinical Diagnostics
Insight Article
Insights from leading experts in biotechnology and academia to explore their thoughts on single cell analysis
24 February 2020
Single Cell Analysis
Insight Article
Insights from leading experts in genome editing and synthetic biology industries
24 February 2020
NextGen Omics Series, NGS & Clinical Diagnostics
Insight Article
Bogdan Budnik, Proteomics Facility Head, Harvard Center for Mass Spectrometry & Nikolai Slavov, Professor, Northeastern University
02 January 2020
NextGen Omics Series, Single Cell Analysis
Insight Article
Dr. Ghassan Yehia, Scientific Director, Genome Editing Core Facility, Office of Research Advancement Rutgers
10 May 2018
Genome Editing, NextGen Omics Series

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