BEX Co., Ltd. is a bio-tech company which has been manufacturing electroporators, electrofusion units, and other lifescience equipments, and been providing oligo DNA, peptides, lifescience service like sequencing for over 20 years. Recently, we developed electroporators to make transgenic animals easily and efficiently by use of CRISPR/Cas9 and electroporation, zygote electroporation and i-GONAD (improved-Genome editing via Oviductal Nucleic Acids Delivery).

In zygote electroporation, dozens of zygotes are aligned in the special electrode with Cas9, electroporated and genome-edited at once. In GONAD, when the oviduct is electroporated with Cas9, the zygotes inside the oviduct are also electroporated and genome-edited.

BEX’s electroporators, CUY21EDIT II and Genome Editor^TM, are the best choice for zygote electroporation and i-GONAD because our technology achieves various pulse pattern and output of “constant electrical current,” which fixes electrical current in the impedance change arising from fat rate of each mice during electroporation, so that reproducibility is increased.