Laki Buluwela

Professor of Cancer Medicine
Imperial College London
Following graduation with a BSc and PhD in Biochemistry from the University of London, Professor Laki Buluwela went to the MRC Laboratory of Molecular Biology in Cambridge, working with Professor Terry Rabbitts, FRS and Nobel Laureates Dr ?Cesar Milstein and Professor Greg Winter. Professor Buluwela has been interested in developing in vitro models for the study of mammary gland morphogenesis and growth, using primary and malignant human mammary epithelial cells. His current work has centred on developing new techniques for manipulating key genes in such cell models and has been carried out in collaboration with Professor Simak Ali and Professor Charles Coombes at Imperial College London, where he himself is based. Recently, he has successfully used CRISPR-Cas9 based genome engineering to develop gene knockins and knockouts in breast cancer cell lines, for the study of breast cancer and the mechanisms of resistance to endocrine therapies used in the treatment of the disease.

Sessions

November 7 2019, 16:50
 - 17:20
Using Genome Editing In The Modelling Aspects Of Breast Cancer