Joke holds degrees of Master in Bio-engineering and Master in Applied Computer Science from the Vrije Universiteit Brussel. She obtained her PhD in Applied Biological Sciences in the VIB Switch Laboratory (prof. Frederic Rousseau, prof. Joost Schymkowitz) from the same university. Her PhD research focused on the role of protein aggregation in human disease. As a postdoctoral researcher, Joke worked at the Vesalius Research Center (VIB / KULeuven), where she worked on whole genome sequencing of ovarian and endometrial cancer samples. Joke joined Janssen in 2012 and has been responsible for the computational analysis of ‘omics data supporting early discovery projects in various roles. Currently she is leading a small team of computational biologists, with a strong focus on single cell technologies.