Hendrik Marks obtained his PhD from Wageningen University in genomics and transcriptomics of White Spot Syndrome Virus. In 2006 he joined the department of Molecular Biology at Radboud University Nijmegen to initiate epigenetic profiling of mouse embryonic stem cells (Cell 2010, Nature 2011, Cell 2012). In 2013, Hendrik obtained the prestigious NWO VIDI grant to establish his own research group. During the last five years, the Marks' lab has focused on the characterization of the epigenome of the transition of mouse embryonic stem cells (mESCs) towards priming as a model for embryonic development (Cell Stem Cell 2013, Cell Stem Cell 2019). Furthermore, they identified topologically associating domains (TADs) as essential regulatory elements of X inactivation, a key event during priming of female mESCs (Genome Biology 2015) and pioneered epigenetic methodologies to profile ultra-low input samples such as obtained during embryogenesis (Nature Communications 2019). The expertise of the Marks' lab in pluripotency and epigenetics is widely acknowledged by the scientific community, as illustrated by a range of high-impact collaborative papers published with leading chromatin biologists (e.g. Cell Reports 2014, Development 2017, Nature Genetics 2018, Nature Cell Biology 2019). Next to his research activities, Hendrik is program coordinator of the University Master "Medical Biology" at Radboud University Nijmegen with ~150 MSc students starting each year. He is a frequent reviewer for academic journals and funding agencies, and member of a range of evaluation committees such as within the Dutch Science Organization and the European Union (Horizon2020).