Anna Reyners

Principal Investigator
University Medical Center Groningen
An Reyners is a medical oncologist. Among others, she is specialized in the treatment of patients with sarcoma. Gastrointestinal stromal tumours (GISTs) are a rare variety of sarcoma. GISTs are characterized by an oncogenic driver mutation in cKIT or PDGFRalpha. This mutation can be detected by analysis of ctDNA. Reyners and colleagues have set up a Dutch biodatabank containing longitudinal, prospective collected ctDNA samples of hundreds of patients with GIST. With a special designed drop off ddPCR known KIT exon 11 mutations of patients with GIST can be detected in serum. Moreover, based on ctDNA analysis of serum the diagnosis of GIST has been made in a few patients in whom a tumour biopsy was not feasible at that moment.

Sessions

November 7 2019, 18:20
 - 18:50
Droplet Digital PCR In Clinical Practice For Patients With A Gastrointestinal Stromal Tumor

Live Webinar

Higher Quality Nucleic Acid Extraction from FFPE Tissue & Other Challenging Samples Using the Ionicâ„¢ Purification System

hosted by Klint Rose, Chief Scientific Officer, Purigen Biosystems

Wednesday 27th May
16:00 BST