Specialized immunohistochemical staining approaches utilized during preclinical and clinical drug discovery research provide valuable insights into the location and positioning of immuno-oncology biomarkers within the tumour and the tumour microenvironment (TME).
Concept Life Sciences has one of the largest chemistry groups in the UK working from state-of-the-art laboratories. They offer a comprehensive range of chemistry services to their clients and design and expedite routes to even the most challenging of targets.
Cell signaling via G-protein coupled receptors (GPCRs), and the downstream cellular processes, cause changes to cell attachment and morphology detectable through impedance measurements. Here, using the Maestro Z platform, we studied the dynamic response of Calu-3 cells to Isoproterenol, Histamine, and Cytochalasin D, revealing important information on the kinetics and mechanism of action for each treatment.
Mixed Lymphocyte Reaction (MLR) assays are commonly used to understand the effects of biologic and small molecule therapeutics on T cell activation - an important response in the tumor microenvironment (TME)
We produce cutting edge congresses and summits for the Life Sciences Industry, bringing together industry leaders and solution providers at a senior level, creating the opportunity to partner, network and knowledge share.