Resources
The latest in drug discovery, from novel targets and screening tools through to automation and computational chemistry
Through captivating articles, insight pieces, and spotlight interviews, we delve into the remarkable innovations, breakthroughs, and scientific marvels that have defined the landscape of research over the past year.
Organ Modelling Discovery
Spheroids, Assembloids Could Unlock High Throughput Screening of Neuro Drugs
These spheroids can mimic different sections of the human brain based on their cell-type composition, and promisingly could enable high-throughput screening of neurology drugs.
Organ Modelling Discovery
Vascular Organoids used to Model the Impact of COVID-19 on Circulation
Researchers have used vascular organoids to look at the impact of SARS-CoV-2 on blood circulation, which has led to the discovery of a potential therapeutic target.
Organ Modelling Discovery
Experts Discuss Next Generation Organoids: Challenges and the Future
How do scientists secure the tissue they need? Should scientists be careful with the words they use for next generation technologies? And why is validation for organ modelling so important?
Organ Modelling Discovery
Changing How We Look at Tumours
Building 3D cell culture models for predictive in vivo and translational results
Organ Modelling Discovery
Cultrex™ Extracellular Matrix And Proteins
CultrexTM Basement Membrane Extract (BME)
Organ Modelling Discovery
Scientists Create Transparent Mouse to Advance Preclinical Medicine
The method, known as tissue clearing and immunolabeling, enables the detection of tumours at the single-cell level.
Organ Modelling Discovery
Newcells Products and Services
We build custom, functional in vitro models, mimicking in vivo physiology, to improve clinical translation and accelerate drug discovery
Organ Modelling Discovery
Cultrex™ Products for Physiologic Cell Culture
R&D Systems products for physiologic cell culture recreate tissue microenvironments to elicit in vivo structure and function for cells in vitro.
Organ Modelling Discovery
Biotechne: Proteins for Stem Cell Culture
Optimize your stem cell cultures with r&d systems™ cytokines and growth factors.
Organ Modelling Discovery
Addressing the Challenges of Cell Models in Research and Drug Discovery
The complexities of developing cell models and testing novel therapies: considering throughput, consistency, and reproducibility.
Organ Modelling Discovery
Host Microbiome Interactions in Inflammatory Bowel Disease
In conversation with Dr Neil McCarthy, MRC Career Development Fellow, Centre for Immunobiology, The Blizard Institute, Queen Mary University of London.
Organ Modelling Discovery
Cerebral Organoids: the Sci-Fi Organ Model Explaining our Brains
These miniature brain replicas, cultivated from patient-derived stem cells, provide a unique window into the intricacies of brain development.
Organ Modelling Discovery
The building blocks of organoid research
Organoid models include three-dimensional (3D) cell culture systems that closely resemble in vivo organs or tissues.
Organ Modelling Discovery
Ex Vivo Propagation in a Novel 3d High?throughput Co?culture System For Multiple Myeloma
Multiple myeloma (MM) remains an incurable hematologic malignancy which ultimately develops drug resistance and evades treatment. Despite substantial therapeutic advances over the past years, the clinical failure rate of preclinically promising anti-MM drugs remains substantial.
Organ Modelling Discovery
PeproGMP Cytokines
Helping unlock the promise of cellular therapies and regenerative medicines.
Organ Modelling Discovery
A Tumor-on-a-Chip System with Bioprinted Blood and Lymphatic Vessel Pair
A 2D model cannot accurately replicate the intricacies of tumor microenvironments, leading to difficulty in identifying effective anticancer drugs.
Organ Modelling Discovery
Allevi 3 Our Most Versatile Lab Adapted Bioprinter
Bring your work to life.
Organ Modelling Discovery
Allevi Bioprinting Customized Solutions
We are the ABCS of Bioprinting! Full service Bioprinting Solutions: Bioprinters | Biomaterials | Bioprinting Consultation
Organ Modelling Discovery
Next Generation 3D Cell Technologies Assays, Services & Products
CoSeedis™ Assays
Organ Modelling Discovery
Organoids: Opening New Doors for Cancer Research
Organoids are three-dimensional tissue cultures grown from stem cells. They have been among the most important and exciting developments in medical sciences in the last decade.
Organ Modelling Discovery
Differentiation of embryonic and induced pluripotent stem cells
Pluripotent stem cells possess the capacity for indefinite self-renewal and the potential to differentiate into all adult cell types of the three primary germ layers.
Organ Modelling Discovery
Generate Physiologically Relevant Airway Cultures
Culture primary human airway epithelial cells as organoids or at the air-liquid interface with the PneumaCult™ media system.
Organ Modelling Discovery
Guide to Sodium Alginate Bioprinting
Four protocols for bioprinting alginate using the Allevi by 3D Systems Platform.
Organ Modelling Discovery
Achieving the Gold Standards of Organ Modelling: Complexity, Robustness, and Reproducibility
We hear the opinions of organ modelling experts on navigating three concepts which are critical to the field: complexity, robustness, and reproducibility.
Organ Modelling Discovery
Using Organs-on-Chips to Catch Kidney Toxicity in Drug Discovery
AstraZeneca have been using the technology to evaluate drug-induced nephrotoxic effects
Organ Modelling Discovery
FDA Can Deem Animal Testing of Drugs No Longer Necessary
For the first time since 1938, the FDA will no longer require animal modelling for drugs to enter clinical trials after a new Act is passed.
Organ Modelling Discovery
Lab on a Chip
A deep conical agarose microwell array for adhesion independent three-dimensional cell culture and dynamic volume measurement
Organ Modelling Discovery
Axion: Neural Organoids
Three-dimensional induced pluripotent stem cell (iPSC)-derived in vitro cell models, commonly referred to as spheroids, organoids, or “mini-brains”, more accurately recapitulate the multicellular organization and structure of in vivo tissues when compared to traditional monolayer cell cultures
Organ Modelling Discovery
Cellesce: Colorectal Cancer Organoid Lines
Cellesce’s technology enables the growth and expansion of Patient-Derived Organoids (PDOs)
Organ Modelling Discovery
Multivascular Networks and Functional IntravascularTopologies within Biocompatible Hydrogels
Modeling multidimensional vascular networks is a notoriously difficult task, especially when considering the complex functions they perform within organ systems.
Organ Modelling Discovery
3D CoSeedis Modular Multi-Purpose 3D Cell Co-Culture System
3D CoSeedisTM from abc biopply ag is a novel scaffold-free 3D cell co-culture system.
Organ Modelling Discovery
Organ-on-a-Chip Market Will Grow at 21.3% CAGR, Predicts Roots Analysis in 2022-2035 Forecast
The organ modelling technology is making a splash in Roots Analysis market predictions, with recent waves of research grants and patents.
Organ Modelling Discovery
Airway Research: PneumaCult™ Culture Media for Human Airway Epithelial Cells
In Vitro Human Airway Model Systems
Organ Modelling Discovery
Biotechne: Brain Organoid Starter Pack
Organoids and 3D cell cultures are emerging as pivotal systems for understanding human organ development, modeling disease, screening for drug efficacy or toxicity, and personalized medicine.
Organ Modelling Discovery
Cellesce: Organoids
Cellesce specialises in the development, scale up and manufacture of patient-derived organoids(PDOs), which will potentially revolutionise life science drug discovery and development for the benefit of human health.
Organ Modelling Discovery
Biotechne: Lung Organoid Starter Pack
Organoids and 3D cell cultures are emerging as pivotal systems for understanding human organ development, modeling disease, screening for drug efficacy or toxicity, and personalized medicine
Organ Modelling Discovery
PeproTech: Organoids
Organoid models include three-dimensional (3D) cell culture systems that closely resemble the in vivo organ or tissue from which they are derived.
Organ Modelling Discovery
PeproTech: The Building Blocks for Organoid Research
Organoid models include three-dimensional (3D) cell culture systems that closely resemble in vivo organ or tissue.
Organ Modelling Discovery
Pavone High Throughput Mechanical Screening Platform
3D tissue models are revolutionizing diagnostics, drug development, and regenerative medicine fields.
Organ Modelling Discovery
Biotechne: Product Portfolio Overview
Partnering with you to drive discovery
Organ Modelling Discovery
Validating Cellesce’s Bioreactor Technology for the Expansion of Patient-derived Breast Cancer Organoids
Cellesce develops bioprocessing systems for the expansion of organoids in significant volumes in a way that minimises handling time and maximises reproducibility, with the long term goal of positioning organoid technology as a cost effective model for early-stage drug discovery.
Organ Modelling Discovery
Organoids: Robust Media to Culture Intestinal, Hepatic, Pancreatic, Kidney, Airway, and Cerebral Organoids
One of the most impactful advances in stem cell research of the past decade has been the development of organoid culture techniques.
Subscribe to Our Newsletter
Sign up for our monthly newsletter to
keep up with all things discovery