Resources

The latest in drug discovery, from novel targets and screening tools through to automation and computational chemistry

Organ Modelling Discovery

Spheroids, Assembloids Could Unlock High Throughput Screening of Neuro Drugs

These spheroids can mimic different sections of the human brain based on their cell-type composition, and promisingly could enable high-throughput screening of neurology drugs.
Organ Modelling Discovery

Vascular Organoids used to Model the Impact of COVID-19 on Circulation

Researchers have used vascular organoids to look at the impact of SARS-CoV-2 on blood circulation, which has led to the discovery of a potential therapeutic target.
Organ Modelling Discovery

Experts Discuss Next Generation Organoids: Challenges and the Future

How do scientists secure the tissue they need? Should scientists be careful with the words they use for next generation technologies? And why is validation for organ modelling so important?
Organ Modelling Discovery

Changing How We Look at Tumours

Building 3D cell culture models for predictive in vivo and translational results
Organ Modelling Discovery

Cultrex™ Extracellular Matrix And Proteins

CultrexTM Basement Membrane Extract (BME)
Organ Modelling Discovery

Scientists Create Transparent Mouse to Advance Preclinical Medicine

The method, known as tissue clearing and immunolabeling, enables the detection of tumours at the single-cell level.
Organ Modelling Discovery

Newcells Products and Services

We build custom, functional in vitro models, mimicking in vivo physiology, to improve clinical translation and accelerate drug discovery
Organ Modelling Discovery

Cultrex™ Products for Physiologic Cell Culture

R&D Systems products for physiologic cell culture recreate tissue microenvironments to elicit in vivo structure and function for cells in vitro.
Organ Modelling Discovery

Biotechne: Proteins for Stem Cell Culture

Optimize your stem cell cultures with r&d systems™ cytokines and growth factors.
Organ Modelling Discovery

Addressing the Challenges of Cell Models in Research and Drug Discovery

The complexities of developing cell models and testing novel therapies: considering throughput, consistency, and reproducibility.
Organ Modelling Discovery

Host Microbiome Interactions in Inflammatory Bowel Disease

In conversation with Dr Neil McCarthy, MRC Career Development Fellow, Centre for Immunobiology, The Blizard Institute, Queen Mary University of London.
Organ Modelling Discovery

Cerebral Organoids: the Sci-Fi Organ Model Explaining our Brains

These miniature brain replicas, cultivated from patient-derived stem cells, provide a unique window into the intricacies of brain development.
Organ Modelling Discovery

The building blocks of organoid research

Organoid models include three-dimensional (3D) cell culture systems that closely resemble in vivo organs or tissues.
Organ Modelling Discovery

Ex Vivo Propagation in a Novel 3d High?throughput Co?culture System For Multiple Myeloma

Multiple myeloma (MM) remains an incurable hematologic malignancy which ultimately develops drug resistance and evades treatment. Despite substantial therapeutic advances over the past years, the clinical failure rate of preclinically promising anti-MM drugs remains substantial.
Organ Modelling Discovery

PeproGMP Cytokines

Helping unlock the promise of cellular therapies and regenerative medicines.
Organ Modelling Discovery

A Tumor-on-a-Chip System with Bioprinted Blood and Lymphatic Vessel Pair

A 2D model cannot accurately replicate the intricacies of tumor microenvironments, leading to difficulty in identifying effective anticancer drugs.
Organ Modelling Discovery

Allevi 3 Our Most Versatile Lab Adapted Bioprinter

Bring your work to life.
Organ Modelling Discovery

Allevi 2 Small but MIGHTY

Bring your work to life.
Organ Modelling Discovery

Allevi 1 Designed to do MORE for less

Bring your work to life.
Organ Modelling Discovery

Allevi Bioprinting Customized Solutions

We are the ABCS of Bioprinting! Full service Bioprinting Solutions: Bioprinters | Biomaterials | Bioprinting Consultation
Organ Modelling Discovery

RepliGut® Custom Services

Recreating the human intestinal epithelium.
Organ Modelling Discovery

RepliGut® Planar Kits

Recreating the human intestinal epithelium.
Organ Modelling Discovery

RepliGut® Model Systems

Recreating the human intestinal epithelium.
Organ Modelling Discovery

Organoids: Opening New Doors for Cancer Research

Organoids are three-dimensional tissue cultures grown from stem cells. They have been among the most important and exciting developments in medical sciences in the last decade.
Organ Modelling Discovery

Differentiation of embryonic and induced pluripotent stem cells

Pluripotent stem cells possess the capacity for indefinite self-renewal and the potential to differentiate into all adult cell types of the three primary germ layers.
Organ Modelling Discovery

Generate Physiologically Relevant Airway Cultures

Culture primary human airway epithelial cells as organoids or at the air-liquid interface with the PneumaCult™ media system.
Organ Modelling Discovery

Guide to Sodium Alginate Bioprinting

Four protocols for bioprinting alginate using the Allevi by 3D Systems Platform.
Organ Modelling Discovery

Achieving the Gold Standards of Organ Modelling: Complexity, Robustness, and Reproducibility

We hear the opinions of organ modelling experts on navigating three concepts which are critical to the field: complexity, robustness, and reproducibility.
Organ Modelling Discovery

Using Organs-on-Chips to Catch Kidney Toxicity in Drug Discovery

AstraZeneca have been using the technology to evaluate drug-induced nephrotoxic effects
Organ Modelling Discovery

FDA Can Deem Animal Testing of Drugs No Longer Necessary

For the first time since 1938, the FDA will no longer require animal modelling for drugs to enter clinical trials after a new Act is passed.
Organ Modelling Discovery

Lab on a Chip

A deep conical agarose microwell array for adhesion independent three-dimensional cell culture and dynamic volume measurement
Organ Modelling Discovery

Axion: Neural Organoids

Three-dimensional induced pluripotent stem cell (iPSC)-derived in vitro cell models, commonly referred to as spheroids, organoids, or “mini-brains”, more accurately recapitulate the multicellular organization and structure of in vivo tissues when compared to traditional monolayer cell cultures
Organ Modelling Discovery

Cellesce: Colorectal Cancer Organoid Lines

Cellesce’s technology enables the growth and expansion of Patient-Derived Organoids (PDOs)
Organ Modelling Discovery

Multivascular Networks and Functional IntravascularTopologies within Biocompatible Hydrogels

Modeling multidimensional vascular networks is a notoriously difficult task, especially when considering the complex functions they perform within organ systems.
Organ Modelling Discovery

3D CoSeedis Modular Multi-Purpose 3D Cell Co-Culture System

3D CoSeedisTM from abc biopply ag is a novel scaffold-free 3D cell co-culture system.
Organ Modelling Discovery

Organ-on-a-Chip Market Will Grow at 21.3% CAGR, Predicts Roots Analysis in 2022-2035 Forecast

The organ modelling technology is making a splash in Roots Analysis market predictions, with recent waves of research grants and patents.
Organ Modelling Discovery

Airway Research: PneumaCult™ Culture Media for Human Airway Epithelial Cells

In Vitro Human Airway Model Systems
Organ Modelling Discovery

Biotechne: Brain Organoid Starter Pack

Organoids and 3D cell cultures are emerging as pivotal systems for understanding human organ development, modeling disease, screening for drug efficacy or toxicity, and personalized medicine.
Organ Modelling Discovery

Cellesce: Organoids

Cellesce specialises in the development, scale up and manufacture of patient-derived organoids(PDOs), which will potentially revolutionise life science drug discovery and development for the benefit of human health.
Organ Modelling Discovery

Biotechne: Lung Organoid Starter Pack

Organoids and 3D cell cultures are emerging as pivotal systems for understanding human organ development, modeling disease, screening for drug efficacy or toxicity, and personalized medicine
Organ Modelling Discovery

PeproTech: Organoids

Organoid models include three-dimensional (3D) cell culture systems that closely resemble the in vivo organ or tissue from which they are derived.
Organ Modelling Discovery

PeproTech: The Building Blocks for Organoid Research

Organoid models include three-dimensional (3D) cell culture systems that closely resemble in vivo organ or tissue.
Organ Modelling Discovery

Pavone High Throughput Mechanical Screening Platform

3D tissue models are revolutionizing diagnostics, drug development, and regenerative medicine fields.
Organ Modelling Discovery

Biotechne: Product Portfolio Overview

Partnering with you to drive discovery
Organ Modelling Discovery

Validating Cellesce’s Bioreactor Technology for the Expansion of Patient-derived Breast Cancer Organoids

Cellesce develops bioprocessing systems for the expansion of organoids in significant volumes in a way that minimises handling time and maximises reproducibility, with the long term goal of positioning organoid technology as a cost effective model for early-stage drug discovery.
Organ Modelling Discovery

Organoids: Robust Media to Culture Intestinal, Hepatic, Pancreatic, Kidney, Airway, and Cerebral Organoids

One of the most impactful advances in stem cell research of the past decade has been the development of organoid culture techniques.

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