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All Discovery Content

Bringing you the latest research in Drug Discovery In New Modalities, Integration Of DEL, Covalent Inhibitors, Protein Degradation Technologies, Computational Drug Design & Automation Strategies and more, through a range of Speaker Interviews, Industry Insights, and Expert Opinions.
Discussion Group Report
The Bioavailability of Oral PROTAC Molecules for ER+ Breast Cancer
Thomas Hayhow, Associate Principal Scientist at AstraZeneca presents his company’s efforts in delivering PROTACs orally.
Edited by Tom Cohen |
25 May 2022
Targeted Protein Degradation
Commentary
PROTACs: “Exciting Opportunities to Explore New Biology”
A Senior Director at AstraZeneca takes us through how the company synthesises and validates novel PROTACs.
Edited by Tom Cohen |
13 May 2022
Targeted Protein Degradation
Insight Article
Getting PROTACs into the Clinic: The Challenges
Oxford Global’s protein degradation panel discussion brought together leading experts in the field to talk about bringing PROTACs to clinical trial endpoints.
Edited by Tom Cohen |
21 April 2022
Targeted Protein Degradation
Discussion Group Report
Protein Degradation – Discussion Group Report
Progress in protein degradation has accelerated in the past few years, and 2021 saw several breakthroughs. Efforts to target STAT3, however, have proven to be especially challenging.
Edited by Oliver Picken |
18 February 2022
Targeted Protein Degradation
Insight Article
Next-Generation Targeted Protein Degradation: Beyond the Usual E3 Ligases
During Discovery Week 2021, Ian Churcher (Chief Scientific Officer at Amphista Therapeutics Limited) gave a fascinating presentation on recent advancements and novel approaches in protein degradation. This article provides a condensed overview of the key topics covered.
Edited by Oliver Picken |
04 February 2022
Targeted Protein Degradation
Video Content
Video Q&A
In Conversation with... Dave Madge
Video Interview | Dave Madge, Vice President, Research Service Division, Wuxi Apptec
22 June 2021
Targeted Protein Degradation
Video Content
Video Q&A
In Conversation... Targeted Protein Degradation
In Conversation with... Sandra Stefanovic-Barrett, Senior Research Scientist, Discovery Biology, Discovery Sciences, Cellular Assay Development, AstraZeneca Yue Xiong, Cheif Scientific Officer, Cullgen
09 March 2021
Targeted Protein Degradation
Video Content
Webinar
Targeted Protein Degradation
Chairman Opening & Remarks by Danette Daniels, PHD, R&D Group Leader of Functional Proteomics, Promega Corp.
Hosted by Kristin Riching, Senior Scientist, Promega & William Farnaby, Team Leader In Medicinal Chemistry And Chemical Biology, University of Dundee
17 June 2020
Targeted Protein Degradation
Written Q&A
Ubiquitin Mediated Small Molecule Induced Target Elimination (USMITE) for Cancer
Michael Plewe, Vice President, Medicinal Chemistry, Cullgen Inc.
02 January 2020
Targeted Protein Degradation

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