Dr. John Karanicolas is a Professor in the Molecular Therapeutics Group at Fox Chase Cancer Center in Philadelphia. He was granted a PhD from Charlie Brooks' lab at The Scripps Research Institute in 2003, for his work using molecular dynamics simulations to study protein folding. He then moved to a postdoc in David Baker's lab at the University of Washington, where he studied protein design and added a wetlab component to his research. He started his lab at the University of Kansas in 2008, focusing on developing structure-based approaches for modulating protein function using small-molecules. He moved his lab to Fox Chase in 2016 to pursue translational applications of his research.