Resources
The latest in omics research, from discovery and multi-omics approaches through to diagnostics development
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Top R&D Stories of 2023
Through captivating articles, insight pieces, and spotlight interviews, we delve into the remarkable innovations, breakthroughs, and scientific marvels that have defined the landscape of research over the past year.
NGS & Clinical Diagnostics
Real-time dynamic single-molecule protein sequencing on an integrated semiconductor device
NGS & Clinical Diagnostics
Comparison of Protein Sequencing Analysis of CDNF, IL6, and FGF2 on Platinum and Mass Spectrometry
NGS & Clinical Diagnostics
Harmonized Multi-Omics Data Analysis - How Does It Impact Pharmaceutical Research?
Harmonized multi-omics data analysis integrates diverse omics disciplines in pharmaceutical research, standardizing protocols for reproducibility and enabling transformative impacts on drug discovery.
NGS & Clinical Diagnostics
Roadblocks to the Sharing of Large Multi-Omics Datasets
More analysis means more data, and sharing multi-omics datasets can present challenges as well as blessings.
NGS & Clinical Diagnostics
Post-Event Proceedings – NextGen Omics US 2023
Concise and insightful summaries of presentations delivered by prominent thought leaders at NextGen Omics US 2023.
NGS & Clinical Diagnostics
Diagnostic Breakthroughs: How Multi-Modal Signatures in Healthcare are Transforming Diagnosis and Treatment
Multi-modal signatures in healthcare combine data from various sources for improved diagnosis and treatment. While offering comprehensive insights, challenges like data integration and ethical concerns need addressing.
NGS & Clinical Diagnostics
AI “Nearly Twice as Good” at Grading Rare Cancer Aggression
New studies have found that AI can outperform humans in grading the aggression and severity of retroperitoneal sarcoma, suggesting big potential for radiomics in cancer diagnosis.
NGS & Clinical Diagnostics
How AI is Opening New Doors in Synthetic Biology and Drug Design
Deep learning and AI are enhancing synthetic biology's role in drug design, emphasising the necessity of quality data in constructing models for approaches such as genome mining and data deconvolution.
NGS & Clinical Diagnostics
The Applications of AI Prediction in Spatial Imaging Approaches
Here, we look at the growing applications of AI-driven spatial imaging techniques in healthcare, focusing on interpreting the 3D genome through cell imaging. AI can assist in understanding intricate data patterns, enabling an improved understanding of cell behaviour and diseases.
NGS & Clinical Diagnostics
Artificial Intelligence in Mammography Could Double Breast Cancer Screening Efficiency
Results from a trial conducted in Sweden – the first of its kind – indicated that the use of AI in mammography screening is safe for general practice, and that this could be a huge boost to radiologists.
NGS & Clinical Diagnostics
Genome Sequencing Approaches: Choosing Between Long-Read and Short-Read Sequencing
Short-read sequencing approaches are highly accurate for small DNA sequences, while long-read sequencing allows for the study of complete genomes without fragmentation. Combining both approaches can address individual constraints and yield more comprehensive results in DNA analysis.
NGS & Clinical Diagnostics
How the $100 Genome Could Reshape the Sequencing Landscape
While the cost of genome sequencing has continued to decrease, the present landscape is still too expensive for the true potential of precision medicine to be fully realised. One potentially revolutionary approach involves the use of a mass-produced item to help reduce costs.
NGS & Clinical Diagnostics
Chronic Stress Found to Worsen Gut Inflammation
Research from the University of Pennsylvania suggests that stress levels may have a profound impact on the efficacy of treatment approaches for bowel disease.
NGS & Clinical Diagnostics
20 Years Ago This Month: Human Genome Project Sequences 92% of the Human Genome
After 13 years of collaborative efforts, an international team of scientists and researchers had an announcement to share with the world. It was one that had major implications for the future of DNA sequencing and healthcare at large.
NGS & Clinical Diagnostics
Untargeted Metabolomics Data Analysis Reinforced by AI/ML Techniques
A key utility of untargeted metabolomics is for detecting key metabolites as indicators of human health and disease status. AI/ML approaches can help to accelerate the verification and validation of metabolomics data.
NGS & Clinical Diagnostics
Asteria - Advanced Single-Cell Analysis in a Straightforward Benchtop Kit
NGS & Clinical Diagnostics
CosMx Spatial Molecular Imager - The First Fully-Integrated Single-Cell Spatial Biology Solution
NGS & Clinical Diagnostics
Genomic Scar Analysis for Homologous Recombination Deficiency with NxClinical Software
NGS & Clinical Diagnostics
PIPseq Reveals Neuronal and Glial Cell Diversity in Freshly Dissociated Mouse Brain
NGS & Clinical Diagnostics
Spatial Profiling of Immune Cell Gene Signatures in the Tumour Microenvironment
NGS & Clinical Diagnostics
Long-Read Sequencing Named 'Method of the Year 2022'
Powering a more complete reading of genomic information, Nature hails long-read sequencing as the omics-based method of the year.
NGS & Clinical Diagnostics
FDA Clears Genomic Profiling Test for Solid Tumours
Regulatory approval for comprehensive genomic profiling test signifies “significant advancement in personalised cancer care.”
NGS & Clinical Diagnostics
Spatial Analysis of TME Microglia in Melanoma Brain Metastasis
The therapeutic targeting of TME microglia activity may improve the efficacy of treatments for melanoma brain metastasis. Future research could represent a new opportunity in confronting one of the most difficult cancers to treat.
NGS & Clinical Diagnostics
Antibody-Mediated Rejection and Next-Gen Sequencing in Precision Medicine
Maintaining tolerance to a graft or organ transplant is a critical aspect of treatment for precision medicine. Antibody-mediated rejection is a serious hurdle to transplantation success, but the integration of highly selected stem cells into treatment may be a solution.
NGS & Clinical Diagnostics
Data Collection, Image Modelling, and Spatial Analysis: Quality Control for Quality Data
The potential applications of deep learning tools in preliminary studies have developed along with their complexity in the past few years. Now, they could be used to help to refine a study or programme before it takes place in order to optimise its efficiency.
NGS & Clinical Diagnostics
Next Generation Nucleic Acid Extraction for NGS: Increased Yields and More Efficient Workflows for Extraction from FFPE
On-demand seminar. Learn more about the Ionic system and a real-world case study on how the Ionic is being utilized at a leading cancer centre.
NGS & Clinical Diagnostics
Data Integration in Genomic Analysis: Computational Methods for the Integration of Spatial Metabolomics
This Commentary article explores the potential applications which arise from combining multiple modalities of information to augment the spatial resolution of data.
NGS & Clinical Diagnostics
Long and Short Read Sequencing: Revolutions in Genomics Data
In this Discussion Group Report, we investigate some recent applications of long- and short-read sequencing technologies. Continued improvements and advancements in the field mean sequencing errors are increasingly a thing of the past, while the portability of some new units makes them ideal for work in the field.
NGS & Clinical Diagnostics
Paving the Road to Multi Omics Bioinformatics
Our May Omics Series discussion group focused on the current uses and potential of multi-omics bioinformatics.
NGS & Clinical Diagnostics
De Novo Variants: Genomic Sequencing and Problem Solving for Future Treatments
In this Commentary article, we investigate the application of new research techniques to inspecting genomic data for the presence of de novo variants - genetic alterations present for the first time in one individual as a result of a variant inherited from a parent. Used in combination with data from the 100,000 Genome Project, these techniques could reduce the time taken for patients to receive a diagnosis for rare genetic diseases.
NGS & Clinical Diagnostics
Multi-Tissue Molecular Profiling: Precision Medicine for Neurodegenerative Diseases
At NGO US: In-Person 2022, Carlos Cruchaga of the Washington School of Medicine presents on using QTL and GWAS data to unlock the future of therapeutic treatment for neurodegenerative disease.
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