CRISPR-based animal models expedite drug development by enhancing accuracy, replicating human physiology, reducing time and cost, aiding in predicting treatment efficacy, and addressing safety concerns in clinical trials.

To date, 114 Nobel Prizes in Physiology or Medicine have been awarded to 226 laureates. Of these laureates, just 12 have been women. This article looks at one of those 12 women and celebrates her contributions to the field of genetics. Her name is Barbara McClintock.

The human pangenome contains genetic data from 47 people across Africa, Asia, Europe, and the Americas, and offers a more holistic cross-section of the planet’s genetic diversity.

Artificial Intelligence (AI) and accelerated computing enable new frontiers in genome sequencing workflows.

Richard Stanton, Professor of Virology at Cardiff University, presents the latest on and off-target genome editing techniques.

Wellcome Sanger Institute propose a new machine learning algorithm for predicting genome editing efficiency for the CRISPR-Cas9-based approach of prime editing.

In Conversation With Laralynne Pryzbyla, Adjunct Assistant Professor at UCSF & UC Scientific Director, Laboratory for Genomics Research

John Parrington, Associate Professor of Cellular and Molecular Pharmacology & Fellow of Worcester College, University of Oxford, discusses the regulatory challenges and opportunities of genome editing.

Responsible genomics research is vital to ensuring the advancement of health for society. But what are the ethical, social, and legal considerations that go into genomics-based decision making?

A memorandum of understanding has been reached between the U.S. Food and Drug Administration (FDA) and the National Cancer Institute (NCI) to provide a framework for solving complex problems in molecular characterisation and classification of tumours.

The gene editing field has exploded in the last ten years, with methods such as CRISPR-Cas9 becoming well-established in the pre-clinical sphere. However, complications in clinical applications have led some researchers to explore alternatives.

Current and upcoming gene editing technologies, such as prime editing and cell line models, have huge potential in applications such as cancer treatment. With the field constantly witnessing new breakthroughs and advances, genome modification holds a lot of promise for the future.

On-Demand Webinar featuring Dr. Peter Mouritzen, Vice President of Application and Market Development at Samplix ApS

Long Read DNA Sequencing has the potential to help diagnose several diseases and disorders. Recent advancements mean that long-read sequencing is no longer an expensive, low throughput, error-prone process.

Gábor Balázsi, Henry Laufer Professor of Physical and Quantitative Biology at Stony Brook University, takes us through the most valuable features that NextGen Omics US brought us in 2022.

We sat down with the Co-director of Yale Genome Editing Centre of Yale University, Xiaojun Xing, to discuss his breakthrough cryopreservation method and his thoughts on the genome editing landscape.

Our February Omics discussion group focused on novel genome editing and how new technologies are being used to tackle the challenges of transitioning to therapeutic use.

In Conversation With Mike Koob, Associate Professor in the Department of Laboratory Medicine and Pathology at the University of Minnesota

In Conversation With Gabor Balazsi, Henry Laufer Professor, Stony Brook University