Resources

The latest in biomarkers research, from development and diagnostics to precision medicine

Genomic Markers & Precision Medicine

Diagnostic Biomarkers Identified Through Multi-Omic Approaches in Chronic Decline and Crohn’s Disease

Diagnostic biomarkers offer a crucial means of tracking disease spread and progression. Here, we explore their application in age-related diseases, as well as inflammatory diseases such as Crohn’s.
Biomarkers for Clinical Development

Challenges in Improving Patient Outcomes: Why Biomarkers Are Difficult to Commercialise

While biomarkers are integral to the identification and validation of disease treatment methods, there is a disconnect between existing validation approaches and their applications in commercialisation.
Diagnostics

Plasma Biomarkers Show Promise in CNS Trials for Alzheimer's Disease

Proteins in the brain and plasma of individuals with sporadic Alzheimer’s disease are altered, supporting the hypothesis that plasma biomarkers have utility in predicting early onset in cognitively unimpaired populations.
Biomarkers for Drug Discovery & Development

Biomarker Discovery and the Identification of the First Cancer Biomarker

In modern healthcare, biomarkers are an integral part of approaches to monitoring patient health and condition, providing researchers with a means of predicting treatment response. But what was the first biomarker to be discovered?
Diagnostics

ddPCR Approaches for Biomarker Detection and Analysis

The high sensitivity and specificity of ddPCR assays makes the approach well-suited for screening diseases and diagnosing cancer subtypes. Here, we explore some of the ways in which medical researchers are using the technology to pioneer detection of circulating biomarkers for liquid biopsies.
Diagnostics

Blood-Based Biomarkers and Liquid Biopsies in Cancer Treatment: Precision Oncology Approaches and Strategies

Blood is a rich source for biomarker development, and CTCs are increasingly proving themselves to be valuable in cancer prognosis and treatment prediction.
Biomarkers for Drug Discovery & Development

High-Throughput Biomarker Discovery for Clinical Trial Optimization

On-Demand Webinar featuring Dr Mo Jain, Founder & CEO of Sapient

This webinar shares how next-generation, high throughput mass spectrometry, advanced data analysis, and population-scale data are being leveraged for robust discovery of biomarkers that can be used to align patients, disease biology, and therapeutic interventions for clinical trials.
Genomic Markers & Precision Medicine

Biomarkers in Precision Medicine Approaches for Oncology: Overcoming Obstacles to Usage and Uptake 

Precision medicine involves tailoring a therapeutic to a patient’s disease: developing precision therapies require an accurate identification of therapeutic targets from available data.
Diagnostics

High Sensitivity Phenotyping of Extracellular Vesicles by Customized, Single-Molecule Assays

On-Demand Webinar featuring Marina Cretich, Senior Researcher of the National Research Council of Italy at SCITEC-CNR
Biomarkers for Clinical Development

Tumour Heterogeneity and Immune Escape: Circumventing Some of the Biggest Roadblocks in Cancer Treatment

While the complexities associated with identifying tumour state and coordinating an effective immunotherapeutic response are many, pioneering healthcare providers are rising to the challenge.
Biomarkers for Clinical Development

Biomarkers in Psychiatry for Mental Health and Wellbeing

Biomarkers in psychiatry may have the potential to overcome the challenges associated with complications such as depression, bipolar disorder, and generalised anxiety.
Biomarkers for Clinical Development

Improving Approaches for Patient Selection Using Immuno-Oncology Biomarkers

ICIs – immune checkpoint inhibitors – have changed the landscape of therapeutic treatment for cancer and improved survival rates for patients with advanced malignancies. However, the wide variability in clinical response is a significant limitation to treatment.

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