Resources
The latest in biomarkers research, from development and diagnostics to precision medicine
Through captivating articles, insight pieces, and spotlight interviews, we delve into the remarkable innovations, breakthroughs, and scientific marvels that have defined the landscape of research over the past year.
Genomic Markers & Precision Medicine
Diagnostic Biomarkers Identified Through Multi-Omic Approaches in Chronic Decline and Crohn’s Disease
Diagnostic biomarkers offer a crucial means of tracking disease spread and progression. Here, we explore their application in age-related diseases, as well as inflammatory diseases such as Crohn’s.
Biomarkers for Clinical Development
Challenges in Improving Patient Outcomes: Why Biomarkers Are Difficult to Commercialise
While biomarkers are integral to the identification and validation of disease treatment methods, there is a disconnect between existing validation approaches and their applications in commercialisation.
Diagnostics
Plasma Biomarkers Show Promise in CNS Trials for Alzheimer's Disease
Proteins in the brain and plasma of individuals with sporadic Alzheimer’s disease are altered, supporting the hypothesis that plasma biomarkers have utility in predicting early onset in cognitively unimpaired populations.
Biomarkers for Drug Discovery & Development
Biomarker Discovery and the Identification of the First Cancer Biomarker
In modern healthcare, biomarkers are an integral part of approaches to monitoring patient health and condition, providing researchers with a means of predicting treatment response. But what was the first biomarker to be discovered?
Diagnostics
ddPCR Approaches for Biomarker Detection and Analysis
The high sensitivity and specificity of ddPCR assays makes the approach well-suited for screening diseases and diagnosing cancer subtypes. Here, we explore some of the ways in which medical researchers are using the technology to pioneer detection of circulating biomarkers for liquid biopsies.
Diagnostics
Blood-Based Biomarkers and Liquid Biopsies in Cancer Treatment: Precision Oncology Approaches and Strategies
Blood is a rich source for biomarker development, and CTCs are increasingly proving themselves to be valuable in cancer prognosis and treatment prediction.
Biomarkers for Drug Discovery & Development
High-Throughput Biomarker Discovery for Clinical Trial Optimization
On-Demand Webinar featuring Dr Mo Jain, Founder & CEO of Sapient
This webinar shares how next-generation, high throughput mass spectrometry, advanced data analysis, and population-scale data are being leveraged for robust discovery of biomarkers that can be used to align patients, disease biology, and therapeutic interventions for clinical trials.
This webinar shares how next-generation, high throughput mass spectrometry, advanced data analysis, and population-scale data are being leveraged for robust discovery of biomarkers that can be used to align patients, disease biology, and therapeutic interventions for clinical trials.
Genomic Markers & Precision Medicine
Biomarkers in Precision Medicine Approaches for Oncology: Overcoming Obstacles to Usage and Uptake
Precision medicine involves tailoring a therapeutic to a patient’s disease: developing precision therapies require an accurate identification of therapeutic targets from available data.
Diagnostics
High Sensitivity Phenotyping of Extracellular Vesicles by Customized, Single-Molecule Assays
On-Demand Webinar featuring Marina Cretich, Senior Researcher of the National Research Council of Italy at SCITEC-CNR
Biomarkers for Clinical Development
Tumour Heterogeneity and Immune Escape: Circumventing Some of the Biggest Roadblocks in Cancer Treatment
While the complexities associated with identifying tumour state and coordinating an effective immunotherapeutic response are many, pioneering healthcare providers are rising to the challenge.
Biomarkers for Clinical Development
Biomarkers in Psychiatry for Mental Health and Wellbeing
Biomarkers in psychiatry may have the potential to overcome the challenges associated with complications such as depression, bipolar disorder, and generalised anxiety.
Biomarkers for Clinical Development
Improving Approaches for Patient Selection Using Immuno-Oncology Biomarkers
ICIs – immune checkpoint inhibitors – have changed the landscape of therapeutic treatment for cancer and improved survival rates for patients with advanced malignancies. However, the wide variability in clinical response is a significant limitation to treatment.
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